Chemosensory Detection

Chemosensory detection is the process by which organisms detect and interpret chemical signals in their internal and external environments, supporting essential behaviors and physiological responses. Specialized sensory receptors bind molecules such as odorants or tastants, triggering changes in neural activity that are transmitted through sensory pathways to the brain, where the signals are encoded as distinct perceptions. In neuroscience, studying chemosensory detection clarifies how receptor cells, neural circuits, and brain regions transform chemical information into smell, taste, and behavioral responses. This knowledge supports research on sensory disorders, feeding, environmental sensing, and the neural basis of perception.

Chemosensory Detection - Related Videos

Research

JoVE Journal - Behavior
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Automated Analysis of a Nematode Population-based Chemosensory Preference Assay

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Cited by 3 •

2017

We present a behavior recording setup and protocol that enables automated analysis of the nematode, Caenorhabditis elegans' preference for soluble compounds in a population-based assay. This article describes the construction of a behavior chamber, the behavioral assay protocol, and video analysis software usage.

Research

JoVE Journal - Behavior
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Using Enclosed Y-Mazes to Assess Chemosensory Behavior in Reptiles

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Cited by 3 •

2021

Y-mazes enable researchers to determine the relevance of specific stimuli that drive animal behavior, especially isolated chemical cues from a variety of sources. Careful design and planning can yield robust data (e.g., discrimination, degree of exploration, numerous behaviors). This experimental apparatus can provide powerful insight into behavioral and ecological questions.

Research

JoVE Journal - Neuroscience

Assaying Surface Expression of Chemosensory Receptors in Heterologous Cells

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Cited by 6 •

2011

Here we demonstrate a protocol to carry out live cell staining that can be used to detect odorant receptors on the surface of HEK293T cells conveniently. In addition, it may also be used to assay for surface expression of other chemosensory receptors or GPCRs.

Hybridization Chain Reaction RNA Whole-Mount Fluorescence In situ Hybridization of Chemosensory Genes in Mosquito Olfactory Appendages

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Cited by 1 •

2023

The article describes the methods and reagents necessary to perform hybridization chain reaction RNA whole-mount fluorescence in situ hybridization (HCR RNA WM-FISH) to reveal insights into the spatial and cellular resolution of chemosensory receptor genes in the mosquito antenna and maxillary palp.

Combination of Adhesive-tape-based Sampling and Fluorescence in situ Hybridization for Rapid Detection of Salmonella on Fresh Produce

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Cited by 17 •

2010

This protocol describes a simple adhesive-tape-based approach for sampling of tomato and other fresh produce surfaces, followed by rapid whole cell detection of Salmonella using fluorescence in situ hybridization (FISH).

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