Burr Hole Implantation
Burr Hole Implantation - Related Videos
09:02
Application of 3D Printing in the Construction of Burr Hole Ring for Deep Brain Stimulation Implants
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Cited by 3 •
2019
Here, we present a protocol to demonstrate 3D printing in the construction of deep brain stimulation implants.
06:18
A Bedside, Single Burr Hole Approach to Multimodality Monitoring in Severe Brain Injury
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Cited by 1 •
2019
A method of recording multimodality monitoring signals in patients with severe brain injuries using a bedside, single burr hole technique is described.
11:51
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
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Cited by 10 •
2014
An improved method to mechanically test bone anchorage to candidate implant surfaces is presented. This method allows for alignment of the disruption force exactly perpendicular, or parallel, to the plane of the implant surface, and provides an accurate means to direct the disruption forces to an exact peri-implant region.
05:36
Implantation of an Electrode Assembly in a Mouse Brain for Electrophysiological Recording
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2025
This video demonstrates a technique for implanting an electrode assembly into a mouse brain. The assembly contains bipolar electrodes to record activity from the hippocampus and a reference electrode to obtain baseline activity from the cerebellum. An anesthetized mouse is placed on a stereotaxic frame, and the electrode assembly is implanted in the target brain region. The animal is then allowed to recover before performing electrophysiological recording.
01:10
Detection of Black Holes
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2023
Although black holes were theoretically postulated in the 1920s, they remained outside the domain of observational astronomy until the 1970s. Their closest cousins are neutron stars, which are composed almost entirely of neutrons packed against each other, making them extremely dense. A neutron star has the same mass as the Sun but its diameter is only a few kilometers. Therefore, the escape velocity from their surface is close to the speed of light. Not until the 1960s, when the first neutron...
FAQs
Positioning and fixation determine how consistently the implanted device interacts with neural tissue. Researchers place the device near the target region, then secure it so its relationship to the tissue remains stable during recording, stimulation, infusion, or monitoring. This stability is important because movement-related disruption can degrade measurements or interfere with controlled delivery and neural modulation.
The cranial opening provides controlled access while supporting a stable interface between the device and its intended neural location. Maintaining this relationship supports interpretable electrophysiological recordings, localized stimulation, intracranial drug infusion, and pressure monitoring. Stability therefore helps researchers distinguish neural or physiological effects from disruption caused by movement of the implanted device.
Device function determines what the implantation is designed to accomplish. Recording devices measure brain activity, stimulation devices influence neural activity, infusion devices deliver drugs intracranially, and monitoring devices track pressure. Matching the device role to the experimental question allows this access strategy to support measurement, intervention, delivery, or physiological surveillance in vivo.
A typical workflow begins by creating the cranial opening, positioning the selected device near the intended neural region, and securing it in place. Each stage contributes to experimental control: the opening permits access, placement establishes the device-tissue relationship, and fixation helps preserve that relationship. The resulting implant can then support recording, stimulation, infusion, or monitoring.
In neuroscience, Burr Hole Implantation supports studies that require measurements or interventions in a living brain. Electrophysiology can examine neural activity, while stimulation tests the effects of influencing that activity. Intracranial drug delivery and pressure monitoring address other experimental aims. Together, these uses help investigate neural circuits, disease mechanisms, and potential therapies.
The technique is used in both animal models and clinical settings, allowing researchers to examine brain function across experimental and applied contexts. In animal studies, implanted devices can support investigations of neural circuits and disease mechanisms in vivo. Clinical settings extend the approach to monitoring, stimulation, and other research connected with potential therapies.