Olfactory Input Alteration
Olfactory Input Alteration - Related Videos
08:36
Constructing an Olfactometer for Rodent Olfactory Behavior Studies
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Cited by 1 •
2025
This protocol describes the construction of an olfactometer for go/no-go olfactory behavior experiments. Step-by-step instructions, along with images, are provided to ensure the successful construction of the olfactometer. Information for troubleshooting issues encountered during the process is also included.
06:32
Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes
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2017
Olfactory sensory neurons express a wide variety of axon-sorting molecules to establish proper neural circuitry. This protocol describes an immunohistochemical staining method to visualize combinatorial expressions of axon-sorting molecules at the axon termini of olfactory sensory neurons.
07:23
Using Insect Electroantennogram Sensors on Autonomous Robots for Olfactory Searches
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Cited by 49 •
2014
We describe a protocol for using insect antennae in the form of electroantennograms (EAGs) on autonomous robots. Our experimental design allows stable recordings within a day and resolves individual odor patches up to 10 Hz. The efficiency of EAG sensors for olfactory searches is demonstrated in driving a robot toward an odor source.
01:15
Input Efficiency II
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2025
In any production process, resources such as labor and capital must be allocated efficiently to maximize output. When multiple producers rely on the same fixed resources, the challenge is to distribute these inputs in a way that ensures no further improvements can be made without reducing another producer’s output.Efficiency in resource allocation is analyzed using isoquants, which represent different combinations of inputs that produce the same level of output. If an allocation allows at least...
09:00
Olfactory Behavioral Testing in the Adult Mouse
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Cited by 68 •
2009
Fundamental, yet unique properties of the rodent olfactory system have led to its increasing study among biologists. A relatively simple assessment of its function is then also needed. Here we describe sensitive tests for the characterization of mouse olfactory sensitivity and preference.
FAQs
Each manipulation probes a different coding dimension. Changing identity tests how the system distinguishes odors, concentration examines responses to signal strength, timing addresses temporal structure, and mixtures examine combined signals. Comparing these conditions helps separate which features influence activation patterns in olfactory receptor neurons and the olfactory bulb.
Reducing sensory access provides a contrast with changing the odor signal itself. It can show how much neural and behavioral responses depend on incoming information, rather than on the odor’s particular identity, strength, timing, or mixture. This comparison is useful for examining how sensory input shapes perception and related behavior.
Neural responses indicate how altered signals affect brain activity, whereas behavioral responses show whether those changes correspond to perception or action. Examining both measures helps connect odor coding with sensory integration, learning, and perception. The comparison also clarifies whether a change in neural activity is accompanied by a measurable behavioral difference.
Researchers establish controlled odor conditions, vary one or more features such as identity, concentration, timing, or mixture, and then compare neural and behavioral responses across conditions. Including reduced sensory access as a comparison can further clarify the contribution of incoming signals. The resulting contrasts support interpretation of altered activation patterns and behavior.
These experiments can be applied to investigations of navigation, feeding, and social behavior by testing how changed smell signals influence responses in these contexts. The same approach can contribute to studies of disorders that affect smell, linking altered sensory access or odor processing with changes in neural and behavioral outcomes.
By deliberately changing sensory input and observing resulting neural and behavioral responses, this approach offers a way to study how the brain processes information that changes over time or across conditions. Olfactory experiments therefore provide subject-specific evidence for broader questions about sensory representation, integration, and the relationship between input, brain activity, and behavior.