Stroke Neurophysiology
Stroke Neurophysiology - Related Videos
08:23
Standing Neurophysiological Assessment of Lower Extremity Muscles Post-Stroke
0 Views •
Cited by 4 •
2021
This protocol describes the process for performing a neurophysiological assessment of the lower extremity muscles, tibialis anterior and soleus, in a standing position using TMS in people post-stroke. This position provides a greater probability of eliciting a post-stroke TMS response and allows for the use of reduced stimulator power during neurophysiological assessments.
09:16
An Introduction to Neurophysiology
0 Views •
2023
Neurophysiology is broadly defined as the study of nervous system function. In this field, scientists investigate the central and peripheral nervous systems at the level of whole organs, cellular networks, single cells, or even subcellular compartments. A unifying feature of this wide-ranging discipline is an interest in the mechanisms that lead to the generation and propagation of electrical impulses within and between neurons. This subject is important not only for our understanding of the...
09:37
Measurement of Neurophysiological Signals of Ignoring and Attending Processes in Attention Control
0 Views •
Cited by 5 •
2015
Attention control comprises enhancement of target signals and attenuation of distractor signals. We describe an approach to measure separately but concurrently, the neurophysiology of attending and ignoring in sustained intermodal attention, utilizing a passive control condition during which neither process is continuously engaged.
19:32
Preterm EEG: A Multimodal Neurophysiological Protocol
0 Views •
Cited by 39 •
2012
This video explains the background theory of the neonatal EEG activity and the sensory responses, followed by a live demonstration of their recording in neonatal intensive care unit.
07:49
Simultaneous Photothrombosis and Fiber Photometry to Induce and Monitor Ischemic Stroke in Behaving Mice
0 Views •
2025
Using an all-optical approach, ischemic stroke is induced while simultaneously recording neuronal Ca2+ activity using a fluorescent biosensor in the emerging stroke core of an awake, behaving mouse.
FAQs
During ischemic injury, reduced oxygen and glucose limit energy production, making it difficult for neurons to maintain ion gradients. As those gradients become disturbed, electrical signaling and synaptic activity change. These linked effects help explain why neurophysiological measurements can reveal functional disruption beyond the visible lesion.
Hemorrhagic stroke can impair surrounding circuits through pressure and tissue damage, adding mechanical disruption to the functional effects of impaired brain tissue. Ischemic injury primarily emphasizes metabolic failure caused by reduced oxygen and glucose. This distinction matters when interpreting abnormal electrical activity and considering which networks may be impaired during assessment and recovery planning.
Because stroke can disrupt communication across neural networks, recovery depends on more than identifying damaged tissue. Studying changing neurophysiological signals helps show whether coordinated function is returning. This perspective connects neuroscience mechanisms with rehabilitation planning and with treatments intended to promote neural plasticity and restore communication across affected networks.
EEG and evoked potentials help characterize functional changes after stroke and track recovery over time. EEG contributes information about electrical activity, while evoked potentials provide another neurophysiological view of functional responses. Using both approaches can support a broader assessment of how stroke has affected signaling, rather than relying on lesion location alone.
Neurophysiological findings can connect disrupted signaling with practical questions about functional impairment, recovery, and rehabilitation priorities. EEG and evoked potentials are particularly relevant because they can characterize functional changes and track recovery. Their information complements lesion assessment when damaged brain networks are being evaluated for prognosis and rehabilitation planning.
It provides a way to study how vascular injury changes neuronal function, electrical signaling, synaptic activity, and communication across coordinated networks. That knowledge links energy failure and pressure-related tissue effects with measurable brain function. It also guides the development of treatments designed to promote neural plasticity, support recovery, and restore communication across damaged networks.