Vessel Wall Imaging

Vessel wall imaging is a high-resolution technique for visualizing the structure and pathology of blood vessel walls, complementing conventional methods that primarily show the vessel lumen. In intracranial magnetic resonance imaging, black-blood sequences suppress signal from flowing blood, allowing clinicians and researchers to assess wall thickness, remodeling, inflammation, and contrast enhancement. In neuroscience, this approach helps distinguish atherosclerotic plaque, vasculitis, arterial dissection, reversible vasoconstriction, and aneurysm-related changes that may appear similar on luminal imaging. By linking vessel-wall abnormalities with cerebrovascular symptoms, vessel wall imaging supports more precise diagnosis, disease monitoring, and investigation of mechanisms underlying stroke and other neurological disorders.

Vessel Wall Imaging - Related Videos

Research

JoVE Journal - Bioengineering

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

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2012

Stent-induced arterial strain distributions are characterized using an optical surface strain measurement system. This visualization technique is used to gain insights into the impact of stent implantation on the host vessel.

Congo Red Staining to Visualize Amyloid Fibrils in Cerebral Vessel Walls

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2025

The tissue shows amyloid fibrils and abnormal protein aggregates in the cerebral vessel walls, which are key indicators of neurological disorders.

Research

JoVE Journal - Immunology and Infection
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In Vitro and In Vivo Model to Study Bacterial Adhesion to the Vessel Wall Under Flow Conditions

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Cited by 13 •

2015

To study the interaction of bacteria with the blood vessels under shear stress, a flow chamber and an in vivo mesenteric intravital microscopy model are described that allow to dissect the bacterial and host factors contributing to vascular adhesion.

Contrast Enhanced Vessel Imaging using MicroCT

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Cited by 17 •

2011

Contrast enhanced small animal vessel imaging by microCT is a rapid, cost-effective and high-throughput technique for serial in situ examination for tumor development, for analyzing the network of blood vessels that nourish them, and for following the response of tumors to preclinical therapeutic intervention(s).

Culturing and Applications of Rotating Wall Vessel Bioreactor Derived 3D Epithelial Cell Models

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Cited by 80 •

2012

A rotating cell culture system that allows epithelial cells to grow under physiological conditions resulting in 3-D cellular aggregate formation is described. The aggregates generated display in vivo-like characteristics not observed in conventional culture models and serve as a more accurate organotypic model system for a multitude of scientific investigations.

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