Mental Operation Isolation

Mental operation isolation is a psychological research approach that separates a specific cognitive process from other mental activities so researchers can examine its role in behavior. It works by designing tasks that target one operation, such as attention, memory retrieval, decision-making, or mental transformation, while controlling or minimizing competing processes and comparing responses across conditions. This approach helps clarify how cognition is organized, reveals the contributions of distinct operations to performance, and supports the development of more precise models of thinking. In psychology, it can inform research on learning, reasoning, problem-solving, and cognitive changes associated with development or neurological conditions.

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Education

JoVE Science Education - Psychology

Mental Rotation

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2023

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University Visual mental imagery refers to the ability to conjure images in one’s mind’s eye. This allows people to process visual material above and beyond the constraints of a current point-of-view; for example, a person could imagine, using their mind’s eye, how something might look in a different color, or what it would look like if it were made from a different material or rotated and seen from a different perspective. Mental imagery...

Mental Status Examination

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2023

Source: Carmen Black, Matthew Goldenberg, and Jaideep Talwalkar; Yale School of Medicine The mental status exam is a clinical evaluation of emotional, perceptual, and cognitive functioning that spans both the fields of psychiatry and neurology. Developing skill in the psychiatric portions of the examination are important to describe salient aspects of the patient's mental state that may be observed during routine history and/or physical exam. Proficiency in the cognitive portions of this...

Diagnostic and Statistical Manual of Mental Disorders (DSM)

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2026

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, was published in 2013, followed by its text revision, DSM-5-TR, in 2022. This revision incorporates...

Stress and Mental Health

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2025

Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms. Individuals with depression often experience challenges in both their personal and professional...

Research

JoVE Journal - Developmental Biology

Isolation of Human Myoblasts, Assessment of Myogenic Differentiation, and Store-operated Calcium Entry Measurement

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Cited by 11 •

2017

Here, we describe a methodology to obtain a pure population of human myoblasts from adult muscle tissue. These cells are used to study in vitro skeletal muscle differentiation and, in particular, to study proteins involved in Ca2+ signaling.

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