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Journal / Immunology and Infection / Mit den Eizellen
JoVE Journal
Immunology and Infection

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An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Journal (Immunology and Infection)
An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
Intravital Microscopy of the Inguinal Lymph Node
Journal (Immunology and Infection)
Intravital Microscopy of the Inguinal Lymph Node
 
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Mit den Eizellen

Article DOI: 10.3791/3905-v • 09:58 min • June 5th, 2012
June 5th, 2012 •
1, 2, 2, 1
1Institute of Immunology, Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, 2Pathobiology, School of Veterinary Medicine, University of Pennsylvania

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Schistosoma mansoni Eier sind potente Stimulatoren der T-Helferzellen vom Typ 2 (Th2) Immunantwort, die charakteristisch für Parasitenbefall, Asthma und allergische Entzündung. Dieses Protokoll nutzt S. mansoni Ei Injektion an einen CD4 Th2-Zytokin-induzierte Entzündungsreaktion in der Lunge, Lunge durch Granulombildung um das Ei gekennzeichnet, Eosinophilie und Makrophagen-Aktivierung Alternative zu generieren.

Tags

Immunologie Infektionsbiologie Mikrobiologie Helminthen Parasiten Maus Th2- Lungen-Entzündung Granulom alternative Aktivierung Makrophagen
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