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Journal / Developmental Biology / Human pluripotenta stamceller Baserat…
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Developmental Biology

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JoVE Journal Developmental Biology
Human pluripotenta stamceller Baserat Fosterskadande effekter Analyser för kemikaliesäkerhet Screening och systembiologi Data Generation
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Human pluripotenta stamceller Baserat Fosterskadande effekter Analyser för kemikaliesäkerhet Screening och systembiologi Data Generation

Article DOI: 10.3791/52333-v • 17:28 min • June 17th, 2015
June 17th, 2015 •
*1, *2, 1, 1, 1, 3, 3, 4, 2, 1, *2, *1
1Center of Physiology and Pathophysiology, Institute of Neurophysiology, University of Cologne, 2Department of Biology, University of Konstanz, 3Department of Statistics, Technical University of Dortmund, 4Leibniz Research Centre for Working Environment and Human Factors, Technical University of Dortmund
* These authors contributed equally

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De protokoll beskriver två in vitro utvecklingstoxicitets testsystem (UKK och UKN1) bygger på mänskliga embryonala stamceller och transkriptom studier. De testsystem förutse fosterskadande effekter fara människa, och kan bidra till att minska djurstudier, kostnader och den tid som krävs för kemisk säkerhetstester.

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Utvecklingsbiologi mänskliga embryonala stamceller utvecklingstoxicitet neuro neuroektodermal progenitorceller immunoutfällning differentiering cytotoxicitet embryopathy embryoid kropp
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