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诱导小鼠横向主动脉狭窄的闭合胸模型

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A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

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诱导小鼠横向主动脉狭窄的闭合胸模型

DOI:

10.3791/57397-v

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08:10 min

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April 05, 2018

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Lars Eichhorn*¹, Christina Katharina Weisheit*¹, Christopher Gestrich, Konrad Peukert, Georg Daniel Duerr, Muhammad Ajmal Ayub, Felix Erdfelder, Florian Stöckigt

¹Department of Anaesthesiology,University Hospital Bonn, ²Department of Cardiac Surgery,University Hospital Bonn, ³Institute of Physiology 2,University of Bonn, ⁴Department of Medicine – Cardiology,University Hospital Bonn

Chapters

00:04Title
01:01Induction of Anesthesia and Intubation
02:57Preoperative Doppler Measurement and Thoracotomy
04:03Banding the Transverse Aorta
05:58Results: Induction of Successful Transverse Aortic Constriction in Mice
07:30Conclusion

Summary

자동 번역

在这里, 我们提出一个横向主动脉收缩 (TAC) 通过侧开胸手术的协议。该技术是一种微创, 闭合胸部手术的过程, 旨在模拟压力超负荷和心力衰竭的小鼠使用标准的 TAC 实验室设置。

Tags

Transverse Aortic Constriction Murine Closed Chest Model Left Ventricular Myocardial Hypertrophy Minimal Invasive Technique Cardiac Macrophagia Rib Cage Surgical Trauma Anesthesia Intubation Carotid Arteries Doppler Probe

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