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Journal / Immunology and Infection / التعرض لدخان السجائر في الفئران باستخدام نظام…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
التعرض لدخان السجائر في الفئران باستخدام نظام استنشاق الجسم كله
Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses
Journal (Immunology and Infection)
Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses
Generation of Murine Monoclonal Antibodies by Hybridoma Technology
Journal (Immunology and Infection)
Generation of Murine Monoclonal Antibodies by Hybridoma Technology
 
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التعرض لدخان السجائر في الفئران باستخدام نظام استنشاق الجسم كله

Article DOI: 10.3791/61793-v • 06:07 min • October 22nd, 2020
October 22nd, 2020 •
1,2, 3,7, 1,3, 4, 1,5, 6, 6, 2, 4,8, 3,8
1Program in Immunology, Baylor College of Medicine, 2Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, 3Department of Medicine - Immunology Allergy and Rheumatology, Baylor College of Medicine, 4Department of Medicine, Pulmonary, Critical Care, Sleep Medicine, Baylor College of Medicine, 5Department of Pathology and Immunology, Baylor College of Medicine, 6Department of Pediatrics, Research and Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, 7Division of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Sun Yat-sen University, 8Center for Translational Research on Inflammatory Diseases (CTRID), Michael E. DeBakey VA Medical Center

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Click here for the English version.

يوضح هذا البروتوكول دراسة الآثار المرضية الفسيولوجية لدخان السجائر (CS) مع نظام التعرض لاستنشاق الجسم بالكامل (WBI) (WBIS) الذي تم بناؤه داخليا. يمكن لهذا النظام أن يعرض الحيوانات ل CS في ظل ظروف قابلة للتكرار خاضعة للرقابة للبحث عن الآثار بوساطة CS على انتفاخ الرئة وورم الدم.

Tags

علم المناعة والعدوى، العدد 164، دخان السجائر، الهيماتوبويز، انتفاخ الرئة، الجذعية الدموية والخلايا السلف، نخاع العظام، مرض الانسداد الرئوي المزمن
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