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Journal / Cancer Research / Un modèle murin de xénogreffe d’Ommaya pour…
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Un modèle murin de xénogreffe d’Ommaya pour étudier le traitement ciblé direct de la maladie leptoméningée
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Un modèle murin de xénogreffe d’Ommaya pour étudier le traitement ciblé direct de la maladie leptoméningée

Article DOI: 10.3791/62033-v • 07:17 min • January 29th, 2021
January 29th, 2021 •
1,2, 3, 4, 4, 1, 5, 6, 7, 4, 2, 1,2
1Department of Neuro-Oncology, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Comparative Medicine, University of South Florida, 4Department of Breast Oncology, H. Lee Moffitt Cancer Center & Research Institute, 5Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, 6Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, 7Department of Medical Oncology, Roswell Park Comprehensive Cancer Center

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Ici, nous décrivons un modèle de xénogreffe murine qui ressemble fonctionnellement à un réservoir ommaya chez les patients. Nous avons développé le Murine Ommaya pour étudier de nouvelles thérapies pour la maladie leptoméningée universellement mortelle.

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Cancer Research numéro 167 Maladie leptoméningée modèles expérimentaux modèle murin réservoir murin d’Ommaya
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