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iPSC来源心肌细胞中的高通量光学控制和记录钙信号,用于毒性测试和表型药物筛选
 
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iPSC来源心肌细胞中的高通量光学控制和记录钙信号,用于毒性测试和表型药物筛选

Article DOI: 10.3791/63175-v 10:01 min March 31st, 2022
March 31st, 2022

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本协议描述了iPSC来源心肌细胞(iPSC-CMs)中触发细胞活性的全光学控制和观察,用于高通量药物筛选和毒性测试。显示了时间和空间上表型模式的多参数量化。证明了药物在数小时内的长期影响,或数天的顺序测量。

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医学,第181期,
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