Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Songjun Lin; Qiang Lin; Biyi Zhao; Yongchun Jiang; Wanqi Zhuang; Delong Chen; Yajie Zhang; Aijia Chen; Qianrong Zhang; Yuxin Zheng; Jianjun Wang; Fangqiu Xu; Xi Qin; Yefeng Cai

doi:10.3791/63991

고기능 뇌졸중 환자의 인지 결함을 감지하기 위한 이중 작업 스트룹 패러다임

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Neuroscience

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JoVE Journal Neuroscience

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

고기능 뇌졸중 환자의 인지 결함을 감지하기 위한 이중 작업 스트룹 패러다임

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07:42 min

December 16, 2022

DOI: 10.3791/63991-v

Songjun Lin^1,2, Qiang Lin^3,4,5, Biyi Zhao^3,4,6, Yongchun Jiang^3,4, Wanqi Zhuang^3,4, Delong Chen^3,4, Yajie Zhang^3,4, Aijia Chen^3,4, Qianrong Zhang⁷, Yuxin Zheng^3,4, Jianjun Wang¹, Fangqiu Xu⁸, Xi Qin^3,4,9, Yefeng Cai¹⁰

¹Department of Neurology and Psychology, the Fourth Clinical Medical College,Guangzhou University of Chinese Medicine, Shenzhen Traditional Chinese Medicine Hospital, ²Guangzhou University of Chinese Medicine, ³Department of Rehabilitation Medicine,The Fifth Affiliated Hospital of Guangzhou Medical University, ⁴Department of Rehabilitation Medicine,Guangzhou Medical University, ⁵Key Laboratory of Biological Targeting Diagnosis, Therapy and Rehabilitation of Guangdong Higher Education Institutes,The Fifth Affiliated Hospital of Guangzhou Medical University, ⁶School of Traditional Chinese Medicine,Jinan University, ⁷Health College of Guangdong Pharmaceutical University, ⁸Department of Clinical Medicine,Guangzhou Medical University, ⁹Department of Rehabilitation Medicine,Panzhihua Central Hospital, ¹⁰Department of Neurology and Psychology,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine

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Overview

This study introduces a dual-task Stroop paradigm aimed at detecting cognitive dysfunction in high-functioning stroke patients, a group often overlooked by traditional assessment scales. The research evaluates the performance of stroke patients using fNIRS, aiming to enhance clinical assessment and cognitive training methods.

Key Study Components

Area of Science

Neuroscience
Cognitive Assessment
Stroke Rehabilitation

Background

Conventional clinical assessment scales often fail to detect cognitive deficits in high-functioning stroke patients.
Identifying cognitive dysfunction accurately is crucial for effective rehabilitation.
Elevating assessment methods can pave the way for tailored cognitive training.

Purpose of Study

To establish a novel assessment protocol utilizing the dual-task Stroop paradigm.
To identify cognitive deficits that conventional skills miss in high-functioning stroke patients.
To enhance treatment strategies based on cognitive performance metrics.

Methods Used

Utilized fNIRS for real-time brain activity monitoring during cognitive tasks.
Implemented a series of cognitive assessments including MoCA, CDR, and Stroop tasks.
Conducted tests while participants performed specified cognitive tasks, integrating a balance component to evaluate dual-task performance.
Assured participant safety with strict observational guidelines during testing.

Main Results

Stroke patients exhibited longer reaction times and lower accuracy during dual-task evaluations compared to healthy subjects.
Notable differences in brain function metrics were observed, specifically lower beta values in stroke patients.
Results underscore the effectiveness of the dual-task approach in revealing cognitive deficits.

Conclusions

This study establishes a framework for more sensitive cognitive assessment in high-functioning stroke patients.
The dual-task Stroop paradigm may lead to more individualized treatment strategies.
Ultimately, these findings contribute to understanding cognitive mechanisms in stroke recovery.

Frequently Asked Questions

What advantages does the dual-task Stroop paradigm offer?

It allows for the identification of subtle cognitive deficits in stroke patients not detectable by standard assessments, enhancing rehabilitation strategies.

How are cognitive deficits assessed in this study?

Cognitive assessments include MoCA, CDR, and dual-task Stroop tests, measuring attention, memory, and executive function.

What is the role of fNIRS in this protocol?

fNIRS is used to monitor brain activity in real-time while patients perform the Stroop tasks, facilitating a link between cognitive performance and neural correlates.

What safety measures are taken during the assessment?

Participants are observed closely to prevent injuries, particularly when performing dual tasks that involve physical balance.

Can the protocol be adapted for other patient populations?

Yes, the dual-task Stroop paradigm could be modified for use with other neurological conditions where cognitive deficits need identification.

What future research directions does this study suggest?

Future studies should explore different types and difficulty levels of dual tasks to further refine cognitive assessments.

임상 평가 척도는 고기능 뇌졸중 환자의 인지 기능 장애에 충분히 민감하지 않습니다. 이중 작업 패러다임은 인지 기능 장애의 평가 및 인지 훈련에서 이점과 잠재력을 제시합니다. 이 연구는 고기능 뇌졸중 환자의 인지 기능 장애를 식별하기 위한 이중 작업 Stroop 패러다임을 제안합니다.

우리의 연구 프로토콜은 기존의 평가 기술로 쉽게 감지되지 않는 고기능 뇌졸중 환자의 인지 결함을 식별하는 데 사용될 수 있습니다. 이 연구 프로토콜은 고기능 뇌졸중 환자에 대한 일반적인 임상 평가 실패에 미치는 영향을 파악하기 위한 새로운 아이디어를 제공하기 위한 것입니다. 이 연구 프로토콜은 임상 실습에서 쉽게 사용할 수 있습니다.

예를 들어, 임상의는 Stroop 반응 시간과 정확한 속도에 따라 치료 전략을 수정할 수 있습니다. 절차를 시연하는 것은 재활 치료사 인 Siqi Huang이 될 것입니다. Siqing Wang, 작업 치료사; Yajie Zhanga, 물리 치료사, Biyi Zhao, 우리 연구실의 작업 치료사. 영상 검사로 확인된 Brunnstrom Stage 4에서 안정적인 상태의 뇌졸중 환자를 모집합니다.

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