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Circuits numériques géniques basés sur des systèmes CRISPR-CAS et des protéines anti-CRISPR

Article DOI: 10.3791/64539-v • 10:46 min • October 18th, 2022
October 18th, 2022 •
*1, *1, 1
1School of Pharmaceutical Science and Technology, Tianjin University
* These authors contributed equally

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Les systèmes CRISPR-Cas et les protéines anti-CRISPR ont été intégrés dans le schéma des portes booléennes chez Saccharomyces cerevisiae. Les nouveaux petits circuits logiques ont montré de bonnes performances et approfondi la compréhension des facteurs de transcription basés sur dCas9 / dCas12a et des propriétés des protéines anti-CRISPR.

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Rétraction numéro 188 système CRISPR-Cas dSpCas9 denAsCas12a dLbCas12a protéines anti-CRISPR de type II-A protéines anti-CRISPR de type V-A circuits numériques géniques Saccharomyces cerevisiae biologie synthétique
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