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TOPICAL COLLECTIONS

Current Methods in Engineered Living Materials

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Guest Editors

Anna Duraj-Thatte

Anna Duraj-Thatte

Virginia Polytechnic Institute and State University, Department of Biological Systems Engineering

<p>Anna Duraj-Thatte is an Assistant Professor in the Department of Biological Systems Engineering at Virginia Tech. She received her Ph.D. from the Georgia Institute of Technology, wherein she worked on protein engineering and directed evolution. Then she pursued her postdoctoral research at Wyss Institute, Harvard University. Her research focused on developing engineered living materials for various applications, including the first demonstration of therapeutic and self-regenerating functionalities of living materials. Her research interests also include protein-based materials for environmental applications and actively working towards commercialization of her research innovations. She was the Grand Prize Winner of the American National Science Foundation (NSF) Idea Machine competition.</p>

Avinash Manjula Basavanna

Avinash Manjula Basavanna

Northeastern University

<p>Avinash Manjula-Basavanna obtained his PhD in Bioinspired Molecular and Materials Engineering at JNCASR, Bengaluru, India. He then moved to Harvard University as a Wyss Institute Postdoctoral Fellow to work on Engineered Living Materials, wherein he Genetically Engineers Microbes to produce Sustainable Materials with Integrated Life-like Properties. Recently, he moved to Northeastern University along with his PI from Harvard and worked at the Massachusetts Institute of Technology (MIT) as a Research Affiliate. He has made pioneering contributions to the emerging field of Engineered Living Materials, and his research interests are at the interface of Synthetic Biology, Bioinspired Materials Engineering, Nanotechnology, Microbial Factories, and Sustainability. In 2020, he was featured as one of the World&rsquo;s Top 35 Innovators Under 35 by Technology Review, MIT. He was the Grand Prize Winner of the American National Science Foundation (NSF) Idea Machine (Big Idea) competition and was recognized with Deep Tech Pioneer and Gandhian Young Technological Innovation Awards. He was also selected for the Innovation Scholars In-Residence Program by the President of India and Harvard Innovation Lab&rsquo;s Venture Incubation Program. His research work has been highlighted by several global media outlets such as The New York Times, The Washington Post, Smithsonian Magazine, New Scientist, The Naked Scientist, Science Alert, etc.</p>

Collection Overview

Built on the foundations of synthetic biology, materials engineering, and nanotechnology, Engineered Living Materials (ELMs) provide an unprecedented platform for building a sustainable environment. The living cells are being engineered to act as a living factory of biomaterials production or to modulate their properties on demand and enable life-like functions beyond traditional synthetic materials' capabilities. These programmable novel biomaterials can self-regenerate, self-heal, self-regulate and/or dynamically respond to the environment.

This collection comprises a variety of established methods for the bio-fabrication of engineered living materials, namely, living material bioproduction, genetic engineering of different microbes, methods to integrate engineered living cells into polymeric materials, hybrid living materials, additive manufacturing, and various techniques to integrate programmable functions into the engineered living materials.

Articles

3D Printing Bacteria to Study Motility and Growth in Complex 3D Porous Media
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3D Printing Bacteria to Study Motility and Growth in Complex 3D Porous Media

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2024