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Rabies is an acute progressive encephalitis caused by a lyssavirus. The case fatality of this zoonosis is the highest for any infectious disease. Although laboratory tech…
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The Mexican Tetra, Astyanax mexicanus is an excellent model organism to study the developmental and genetic basis of evolution. This species of fish co…
Chloroplasts are the organelles that define plants. Along with many other metabolic, developmental and signalling functions, chloroplasts are responsible for photosynthes…
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The study of protein-protein interactions is key to understanding the network of molecular interactions underlying biological effects, and defining how individual protein…
Integrative structural biology uses a large variety of biophysical methods that provide detailed knowledge of the atomic and molecular structure of macromolecules, isolat…
Prolonged lifespan and delayed childbearing have prompted the research of reliable methods to preserve fertility for later in life. Such interventions that heavily rely o…
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Interdisciplinary problems are increasingly important to researchers from all fields. Due to their multidisciplinary characteristics, such studies should be performed in …
Advancements in ultrasound transducer and computer technology have permitted for the visualization of cardiac structures with excellent spatial and temporal resolution in…
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Cell-free expression (CFE) systems are a collection of methods that use extracted cellular machinery to mimic core functions of cells, such as transcription and translati…
The vertebrate retina is a complex, laminated sensory organ. It consists of multiple neuronal cell types and subtypes which synapse on each other to detect visual informa…
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The sense of taste is essential to preserve a healthy body and mind. While taste contributes to the selection of beneficial compounds over noxious compounds to ensure pro…
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Proteins adopt different higher order structures (HOS) to enable their unique biological functions. Understanding the complexities of protein higher order structures and …
The study of gastrointestinal inflammation and repair is key to elucidate the role of different cell populations and molecules during acute and chronic gut inflammatory p…
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Covering ~40% of the human body, skeletal muscle is a major organ, supporting critical functions ranging from movement and respiration, to metabolism and temperature regu…
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Recent years have seen rapid development of electron microscopy techniques for a variety of fields. The physical sciences, in particular, have seen a large number of tech…
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In vitro culture is a powerful tool for the phenotypic and mechanistic study of retinal function and cellular activities. Classical 2D primary endothelial cell function a…
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The genomics revolution has resulted in a vast amount of knowledge about human physiology and how different diseases affect function. Additional technological advancement…
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Obesity has become a major worldwide public health issue, dramatically increasing the risk of developing cardiovascular disease, type 2 diabetes, and liver diseases. Obes…
The number of manufactured nanomaterials (MNMs) entering the market in everyday products is continuously increasing. These products range from health care to electronics,…
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Acute hippocampal slices have been used for decades by neuroscientists to study neuronal circuits and synaptic properties. This technique has yielded major discoveries, s…
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Cancer research has focused on the cancer cell, its proliferation rates, apoptosis resistance, mutation rates, sensitivity to radio and chemotherapy. However, tumor metas…
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Neurons are the primary cells of the nervous system and are responsible for the distinctive roles of the brain. Understanding the mechanisms that regulate their different…
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Protein homeostasis, or ‘proteostasis’, is fundamental to cellular and organismal health. Conserved cellular processes cooperate to maintain a properly folded…
Neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, amyotrophic lateral sclerosis, and frontotemporal d…
Cardiovascular diseases remain a major health and economic burden worldwide. This is a consequence to the poor regenerative ability of the adult mammalian heart to repair…
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Axons are the main line of information transmission among neurons. Accordingly, axonal pathology represents a common pathogenic feature associated with loss of neuronal c…
Pluripotent stem cells retain the ability to form all cell types in the human body. This provides the field with renewable forms of human tissue, from defined genetic bac…
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Minimally invasive pancreatic surgery is on the rise worldwide. Minimally invasive distal pancreatectomy (MIDP) has been reported to be superior to open distal pancreatec…
Organoids are three-dimensional (3D) ex vivo cellular structures that are believed to recapitulate and maintain the in vivo conditions of cellular viability and responsiv…
International classifications of mental disorders for the diagnosis of Learning Disabilities (LD) and Attention Deficit/Hyperactivity Disorders (ADHD) establish that they…
Nanogels are hydrogels within the nanometres range consisting of crosslinked porous polymer networks with the ability to retain high volumes of water or biological fluids…
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Fungi play vital ecological roles in nature as major nutrient recyclers, establish mutualistic relationships with other organisms, and cause devastating diseases of plant…

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