Guest Editors
Massimo Grilli
University of Genova, Department of Pharmacy, Genoa, Italy
<p>Dr. Massimo Grilli is an Associate Professor in the Department of Pharmacy at the University of Genova. His laboratory focuses on pharmacology at the synaptic level. In particular, he studied the mosaic of receptors and proteins involved in neurotransmitter release in physiological and pathological conditions. Several investigations have been dedicated to the interplay between nicotinic and glutamatergic receptors. Furthermore, Dr. Grilli and collaborators studied the relationship between cholinergic receptors and amyloid peptides as the watershed between physiological and pathological conditions. Recently, his lab implemented several protocols to assess behavioral effects and motor performance in mice.</p>
Guendalina Olivero
University of Genoa, Italy, Department of Pharmacy, Pharmacology and Toxicology
<p>Guendalina Olivero got a degree in Pharmacy in 2010 and a PhD in Pharmacology and Toxicology in 2014 at the University of Genoa. She is currently an assistant professor at the Department of Pharmacy, Pharmacology and Toxicology section of the University of Genoa (Italy). Her research is focused on studying the mechanisms of synaptic transmission, particularly the release of neurotransmitters and its modulation by receptors in physiological and pathological conditions, such as multiple sclerosis, aging, and pain. She is the author of 36 papers published in peer-reviewed international journals and more than 80 congress abstracts.</p>
Collection Overview
Neural nicotinic acetylcholine receptors (nAChRs) are widely recognized as pharmacological targets due to their role in several physiological and pathological processes, such as learning and memory, addiction, pain, neuroinflammation, and neurodegeneration. Understanding the complexity of nAChRs' function is still challenging since they are often part of a "membrane receptor interactome" and cross-talk with other membrane targets (e.g., channels, receptors, and transporters), thereby modulating their functional responses.
The aim of this Methods Collection is to show current methods for investigating this topic. All contributors can help the scientific community improve and standardize these methods.
