Guest Editors
Sanyin Zhang
Chengdu University of Traditional Chinese Medicine, Innovative Institute of Chinese Medicine and Pharmacy
<p>Professor Sanyin Zhang, dean of the Innovative Institute of Chinese Medicine and Pharmacy at Chengdu University of Traditional Chinese Medicine, is a doctoral supervisor. He has long been committed to using the diversified technologies of modern molecular biology, physical chemistry, imaging, and electrophysiology to expound the modern scientific connotation of the Qi-blood theory of traditional Chinese medicine, and uncover the molecular mechanism of ethnic medicine nourishing Qi and promoting blood circulation.</p>
Xianli Meng
Chengdu University of Traditional Chinese Medicine, Innovative Institute of Chinese Medicine and Pharmacy
<p>Xianli Meng received her PhD from the School of Pharmacy at Chengdu University of Traditional Chinese Medicine in 1998. Currently, she is committed to the interpretation of the anti-inflammatory pharmacodynamic substances and the mechanism of drugs as well as evaluating the efficacy and related mechanisms of drugs against hypoxic cardiovascular and cerebrovascular diseases using emerging imaging techniques.</p>
Xiaobo Wang
Chengdu University of Traditional Chinese Medicine, Innovative Institute of Chinese Medicine and Pharmacy
<p>Xiaobo Wang received his MD from the School of Pharmacy at Chengdu University of Traditional Chinese Medicine in 2020. At present, he is working as a Postdoctoral Researcher in the Innovative Institute of Chinese Medicine and Pharmacy at Chengdu University of Traditional Chinese Medicine, focusing on the application of new techniques and methods to the mechanisms of ethnic medicine in the prevention and treatment of hypoxic cardiovascular and cerebrovascular diseases.</p>
Qipeng Zhao
Ningxia Medical University, School of Pharmacy
<p><span style="color: windowtext;">Professor Qipeng Zhao is a Master's program supervisor and a member of the experimental pharmacological association of TCM. He has long been committed to the pharmacology and toxicology of TCM and ethnic medicine to prevent and treat cardiovascular and cerebrovascular diseases. </span></p>
Xiao Ju
Sichuan Scientist Biotechnology Co., Ltd
<p>Xiao Ju<span style="color: windowtext;"> is the CEO of Sichuan Scientist Biotechnology Co., Ltd., responsible for establishing in vitro and in vivo disease models, pharmacodynamic evaluation, and mechanism research. He has been engaged in more than ten years of innovative drug research, development technical services, and market experience. </span></p>
Collection Overview
Mitochondrial morphological and functional abnormalities play a crucial role in various diseases, including high altitude hypoxia-induced brain damage, cardiovascular and cerebrovascular disorders, complications related to diabetes, rheumatoid arthritis, allergic rhinitis, and cancer, among others. The therapeutic efficacy of ethnomedicine in addressing these diseases characterized by mitochondrial injury is noteworthy.
We invite and encourage submissions of manuscripts that employ diverse methodologies to investigate the protective effects of ethnomedicine on mitochondrial health. A wide array of techniques is used in the screening and validating mitochondrial morphology, function, and potential targets affected by ethnomedicine. These techniques include laser confocal imaging, high-content imaging, the Seahorse cell energy metabolism analyzer, surface plasmon resonance (SPR), microscale thermophoresis (MST), bio-layer interferometry (BLI), cellular thermal shift assay (CETSA), differential scanning fluorimetry (DSF), and patch clamp technology.
This Methods Collection comprehensively encompasses studies using animal models, organoids, and cellular models to investigate mitochondrial diseases.
Articles
Protective Effects of Serum Containing Tibetan Medicine Jiangtangle on Mitochondrial Function in RIN-m5F Pancreatic β-Cells
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2025
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Renqing Duojie*1, Min Chen*2,3, Chenghua Li*4, Fu Wang2, Xiaobo Wang5, Xianli Meng3, Nanjia Cairang1, Ya Hou3
1Department of Tibetan Medicine, University of Xizang Medicine, 2School of Pharmacy/School of Modern Chinese Medicine Industry, Chengdu University of Traditional Chinese Medicine, 3TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, 4College of Life Sciences, Sichuan University, 5Innovative Institute of Chinese Medicine and Pharmacy/Academy for Interdiscipline, Chengdu University of Traditional Chinese Medicine