JoVE | Peer Reviewed Scientific Video Journal

TOPICAL COLLECTIONS

Advanced Biomaterials: Fabrication, Functionalization, Characterization, and Biological Evaluation

Guest Editor

Laila A. Damiati

University of Jeddah, Department of Biological Sciences

<p>Dr. Damiati is an associate professor in the College of Science at the University of Jeddah, Saudi Arabia. She received her PhD in tissue engineering from the University of Glasgow, UK, in 2020. Her interdisciplinary research focuses on tissue engineering, biomaterials, microbiology, and advanced manufacturing technologies. Her work investigates cellular interactions with micro- and nanotopographical materials, dynamic cell-responsive surfaces, 2D and 3D scaffolds, and growth factor-organizing interfaces. More recently, her research has focused on 3D-printed biomaterials and the role of scaffold architecture, porosity, and surface characteristics in regulating mammalian cell responses, bacterial adhesion, and biofilm formation. She is particularly interested in developing multifunctional and infection-resistant biomaterials for regenerative medicine and biomedical applications. Her research also explores sustainable functional materials, antimicrobial technologies, and innovative biomaterial strategies for biomedical and food-related applications.</p>

Collection Overview

Advanced biomaterials are increasingly engineered to provide functions beyond conventional structural support, including modulation of cellular behavior, antimicrobial activity, controlled delivery of bioactive agents, and protection of biological systems. Innovations in material fabrication, surface engineering, nanotechnology, additive manufacturing, and biofunctionalization have enabled the development of multifunctional materials with tailored structural, mechanical, biological, and physicochemical properties. However, variability in fabrication, characterization, functionalization, and biological assessment remains a major challenge for reproducibility and translation.

This Topical Collection will highlight innovative and visually reproducible methodologies for the design, fabrication, functionalization, characterization, and biological evaluation of advanced biomaterials. The scope will encompass 3D-printed and porous scaffolds, hydrogels, films, membranes, coatings, nanomaterials, polymeric composites, micro- and nanoengineered systems, and other emerging functional materials.

Particular emphasis will be placed on strategies that integrate material properties with biological functionality, including surface modification, architecture optimization, cell–material and microorganism–material interactions, antimicrobial functionalization, and controlled delivery. Emerging approaches involving nucleic acids, growth factors, peptides, extracellular vesicles, nanoparticles, natural bioactive compounds, and sustainable materials will also be encouraged.

Applications may span tissue engineering, regenerative medicine, wound healing, drug and gene delivery, antimicrobial technologies, biosensing, active and antimicrobial packaging, food-contact materials, and sustainable valorization of agricultural and food waste.

By integrating methodologies across biomaterials science, biotechnology, microbiology, nanotechnology, and biofabrication, this collection aims to provide practical and reproducible protocols that accelerate the development and translation of next-generation functional materials.