Affiliation: University of Pennsylvania

Dr. Deepti Abbey has over a decade of experience in stem cell biology and is currently working as a research scientist, heading the stem cell core at the Institute of Stem cell & Regenerative Medicine at Bengaluru, India.

Deepti completed her PhD from the Indian Institute of Science, Bangalore, studying epigenetic regulation of cardiomyocyte differentiation. During her PhD, she derived the first transgenic mouse iPSC line from non-permissive mice strain in collaboration with scientists from Thermofisher/ Invitrogen. Later, she studied retinal and forebrain organoid differentiation in collaboration with Dr. Sasai’s group and identified the novel role of a gene RSPO2 in mouse neuro-retina differentiation. Deepti joined Daniel Rader’s lab at University of Pennsylvania and developed an improvised method for hepatic organoids from iPS-cells, using CRISPR editing and high throughput screens studies. Deepti got Michael Brown postdoctoral fellowship from GSK, where she worked with GSK in implementing the developed hepatic organoid model for drug screening. She has ample experience in mouse and human stem cell derivation, reprogramming and differentiation to several lineages using monolayer and 3D organoids approach.