Affiliation: University of Massachusetts Chan Medical School, Department of Microbiology and Physiological Systems, Program in Microbiome Dynamics, Program in Systems Biology

Dr. Bucci is an Associate Professor of Microbiology and Physiological Systems. His lab is focused on developing microbiome-based therapeutics to ameliorate infections, inflammatory and neurological disorders. Dr. Bucci is an engineer and computational biologist by training with extensive experience in microbiology and synthetic biology. He applies methods to predict the dynamics of intestinal commensal and enteropathogenic bacteria, and to optimize bacterial consortia that induce an array of anti-inflammatory responses. Further, he drives the development of novel interpretable machine learning methods to link microbiome dynamics with clinical outcome. On the experimental side his lab develops synthetically engineered probiotics that selectively inhibit growth of pathogenic bacteria to precisely eradicate drug-resistant Enterobacteriaceae including Carbapenem Resistant Klebsiella and ESBL-producing E. coli from the gastrointestinal tract. He currently also serves as Associate Editor for ‘Gut Microbes’, ‘mSystems’, and ‘Microbial Cell’.