
Affiliation: Seoul National University, School of Dentistry
Dr. Jin Man Kim is an assistant professor at the School of Dentistry, Seoul National University. He completed an M.D.-Ph.D. course in 2015, majoring in cell biology. One of the major goals of his research is to achieve a comprehensive understanding of the signaling network mediating the epithelial-mesenchymal interaction during the development of epithelial organs. His work focuses on signaling dynamics from the single-cell (microscopic) to the tissue (mesoscopic) scale during developmental process. To monitor signaling dynamics at a single cell and a subcellular level, he utilizes the fluorescent protein-based genetically encoded biosensors the are customized to the specific biological context. In addition to a diverse range of cell lines, diverse types of organ explant cultures from mouse embryos, including those from the lungs, mammary glands, salivary glands, and tooth germ, are frequently used in his research. Using these strategies, he investigates the spatiotemporal effects of a diverse range of signaling messengers on the cytoskeleton and related physical events. Recently, he applied next-generation sequencing technology to determine the genetic background underlying the observed phenomena.