
Affiliation: Amity Institute of Molecular Medicine and Stem Cell Research, Amity University Uttar Pradesh, Noida, India
Dr. Kajal Kanchan obtained PhD in 2011 from University of Tübingen, Germany in the area of Mycobacterial cell signaling and pathogenesis. Subsequently, she worked as a Marie Curie Postdoctoral fellow at University of Debrecen, Hungary, and characterized Human transglutaminase 2 protein, biochemically and structurally. Later, she moved to University of Cambridge, UK, and worked with histone variants and got an exposure in field of transcription and gene regulation. With such diverse background and experience, she established her research niche focusing on gene regulation in mycobacterial pathogenesis. She received the Ramalingaswami Re-entry fellowship from DBT (Department of Biotechnology, Government of India) to work in the area of temperature signaling in mycobacterium and worked at School of Biotechnology, Jawahar Lal University, New Delhi. Later, she moved to Amity Institute of Molecular Medicine and Stem Cell research, Amity University, Noida. The broad goal of her research team is to explore how bacteria sense and respond to changes in the environment. Her team is using M. tuberculosis/M. smegmatis as model organism and trying to decipher the molecular basis of perception and signal transduction and how these regulate the development and virulence of the Mycobacteria. To achieve these goals she is using genomics, proteomics and computational approaches to model transcriptional, post-transcriptional and translational regulation of the pathogen to find novel intervention measures to treat tuberculosis effectively.