Bladder Catheter Implantation
Bladder Catheter Implantation - Related Videos
03:02
Urine Depletion and Bladder Rinsing in Mouse Model: A Catheter-based Procedure to Empty and Wash Murine Urinary Bladder
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2023
In this video, we describe a catheter-based procedure to empty and rinse the urinary bladder of a mouse model. The prepped mouse can then be used for further experimental procedures.
08:08
The Use of Cystometry in Small Rodents: A Study of Bladder Chemosensation
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Cited by 42 •
2012
Cystometry is an efficient technique to measure bladder function of small animals in vivo. The bladder is continuously infused at rates controlled through an intravesical catheter, whereas the urethra is left free for micturition. This allows for repetitive filling and emptying of the bladder, while intravesical pressure and voided volume are recorded.
11:46
Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
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Cited by 19 •
2014
Approximately 3-8 million people in the United States suffer from interstitial cystitis/bladder pain syndrome (IC/BPS), a debilitating condition characterized in part by pelvic pain. In order to study nervous system contributions to the condition, a physiological model of urinary bladder pain is used in mice and rats.
04:28
Modeling Orthotopic Bladder Tumor in Mouse Model: A Procedure for Intravesical Administration of Cancer Cells into Murine Bladder
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2023
In this video, we describe the intravesical procedure of delivering cancer cells into the bladder of a mouse model. This procedure helps generate an orthotopic bladder tumor model that can be used to develop therapeutic strategies.
02:51
Catheter-Associated Urinary Tract Infection in a Mouse Model
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2026
Source: Conover, M. S., et al., J. Establishment and Characterization of UTI and CAUTI in a Mouse Model. J. Vis. Exp. (2015)This video demonstrates the procedure for assembling and implanting a transurethral catheter in a female mouse, followed by bacterial inoculation to establish catheter-associated urinary tract infection and investigate biofilm-mediated host-pathogen interactions.
FAQs
Securement helps keep the catheter positioned for continued access to the bladder, while patency keeps the tube open for drainage, sampling, or measurement. These features are especially important in longitudinal experiments, because a consistently functioning catheter allows researchers to compare observations across multiple time points rather than relying on a single intervention.
Subcutaneous routing provides a way to reach the implanted catheter while reducing interference with normal movement. This supports physiological studies in which activity or behavior could otherwise be disrupted by external tubing. Maintaining access without repeatedly manipulating the urinary tract also helps researchers collect observations from the same subject over time.
The available implantation pathway is a key procedural choice: the catheter may be placed through the bladder wall or advanced through the urinary tract. Both routes establish access to the bladder, but the selected approach is part of how the experiment is organized and may depend on the intended method of access and measurement.
An implanted catheter can support measurements of bladder pressure, urine composition, and urinary function. It may also provide access for studying responses to drugs or disease. Because these observations can be obtained repeatedly, the approach helps connect changes in bladder physiology with experimental treatments or disease-related processes.
The procedure involves placing the catheter through the bladder wall or urinary tract, securing it so access is maintained, and routing it beneath the skin when repeated access is needed. After implantation, the catheter can support controlled drainage, urine sampling, or physiological measurement during subsequent observations.
Its main research value is repeated access in the same subject. Investigators can follow bladder pressure, urine composition, urinary function, or responses to drugs and disease across time without performing a new invasive access procedure for every observation. This design can improve experimental consistency and reduce procedure-related variation between measurements.