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Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
JoVE Journal
Medicine
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JoVE Journal Medicine
Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
DOI:

11:46 min

April 27, 2014

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Chapters

  • 00:00Title
  • 02:49Surgical Implantation of Urinary Bladder Catheter and Wire Electrodes
  • 06:15Anesthesia Step Down
  • 06:43EMG Recording During Bladder Distention
  • 08:12Analysis of Raw EMG Traces
  • 10:08Results
  • 11:08Conclusion

Summary

Automatic Translation

Approximately 3-8 million people in the United States suffer from interstitial cystitis/bladder pain syndrome (IC/BPS), a debilitating condition characterized in part by pelvic pain. In order to study nervous system contributions to the condition, a physiological model of urinary bladder pain is used in mice and rats.

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