Population Regulation

Population regulation is the set of biotic and abiotic processes that limit changes in population size, helping maintain populations within the conditions their environments can support. These processes often operate through density-dependent feedback: as population density rises, competition for food, space, and mates, along with disease and predation, can increase mortality or reduce reproduction, whereas low density may ease these pressures. In biology, population regulation helps explain fluctuations, carrying capacity, and species distribution, while density-independent factors such as drought, fires, or storms can also alter abundance. Understanding these interactions supports conservation planning, wildlife management, ecosystem research, and predictions of how populations may respond to environmental change.

Population Regulation - Related Videos

Education

JoVE Lab Manual - Biology

Population Growth - Student Protocol

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2019

Exponential Population Growth Model ExpandNOTE: In these experiments you will use computer software to simulate different types of growth models. HYPOTHESES: The experimental hypothesis might be that if we increase either R, the reproductive rate or the initial population size, NT, that this will increase the population size after 10 generations in an exponential growth model compared to unmanipulated control populations. The null hypothesis may be that populations of different R and initial...

Population Growth - Concepts

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2019

Population Models An ecological population is a group of individuals of a single species living in an area at the same time. To persist, a population must either grow or maintain its size. Population ecology is the study of how population size and age distribution change over time through interactions with other species and the environment as well as with individuals of their own species. A particularly important feature that is studied by ecologists is the rate at which a population grows or...

GTPases and their Regulation

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2020

Guanine nucleotide-binding proteins (G-proteins), also known as GTPases, are a superfamily of proteins that regulate many cellular processes, such as cell signaling, vesicular transport, and the regulation of cell shape and motility. Mutation or dysfunction of these proteins can lead to disease. There are around 40,000 known G-proteins that can broadly be classified into two groups ‒ small G-proteins consisting of a single domain and large multi-domain G-proteins. Large G-proteins, also known...

Research

JoVE EoE - Leukemia

Side Population Assay: A Method to Isolate Side Population of Tumor Cells from Zebrafish

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2023

The following protocol describes a method for isolating the side population of T-cell Acute Lymphoblastic Leukemia (T-ALL) tumor cells, consisting of stem cells, from an adult Zebrafish. The side population lacks prominent cell markers and hence we use Hoechst 33342 dye efflux assay to isolate them.

Regulated Protein Degradation

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2020

It is vital to regulate the activity of enzymatic as well as non-enzymatic proteins inside the cell. This can be achieved either through creating a balance between their rate of synthesis and degradation or regulating the intrinsic activity of the protein. Both these regulation mechanisms play an essential role in the normal functioning of cells. Protein degradation plays two important roles in the cells. It helps to protect cells from misfolded or damaged proteins before they lead to a...

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