Isothermal Compression

Isothermal compression is the reduction of a gas’s volume while its temperature remains constant, a process that links pressure, volume, heat transfer, and molecular motion in thermodynamics. For an ideal gas, pressure rises as volume decreases according to Boyle’s law, while compression work is transferred out as heat to maintain constant temperature through thermal contact with the surroundings. In chemistry, this process helps analyze gas behavior, calculate work and heat, compare thermodynamic pathways, and understand gas storage and compression, where temperature control influences pressure, efficiency, and safety.

Isothermal Compression - Related Videos

Education

JoVE Core - Physics

Isothermal Processes

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2025

A thermodynamic process that occurs at constant temperature is called an isothermal process. Heat slowly flows into the system or out of the system to maintain thermal equilibrium. Processes involving phase changes like water evaporation into steam or freezing water into ice at a constant temperature are examples of Isothermal Processes. An ideal gas can also undergo isothermal expansion or compression. For example, consider 1 mole of an ideal gas inside an isolated cylinder at initial volume V...

Compression Tests on Hardened Concrete

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2023

Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA There are two distinct stages in a construction project involving concrete. The first stage involves batching, transporting, and casting fresh concrete. At this stage, the material is viscous, and the workability and finishability are the key performance criteria. The second stage occurs when the hydration process begins shortly after the concrete is placed in the form, and the concrete will...

Research

JoVE EoE - Bacterial Growth and Techniques

Loop-Mediated Isothermal Amplification for Bacterial Gene Detection

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2025

Source: Domesle, K. J., et al. Loop-Mediated Isothermal Amplification for Screening Salmonella in Animal Food and Confirming Salmonella from Culture Isolation. J. Vis. Exp. (2020).This video demonstrates the loop-mediated isothermal amplification (LAMP) technique for detecting a target bacterial gene by amplifying DNA at a constant temperature. The reaction mixture is prepared by adding an isothermal master mix, specific primers for the target gene, and samples containing DNA templates. The...

Isothermal Microcalorimetry to Monitor Metabolic Activity in Bacteria

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2025

Take serial dilutions of a bacterial culture and add aliquots into calorimetric vials containing growth medium.Load the sealed vials into the multi-well plate of an isothermal microcalorimeter to measure metabolic heat production.The device is held at a constant temperature to ensure the detected heat originates solely from bacterial metabolism.As bacteria metabolize nutrients and proliferate, they release heat that sensors detect in real time.In parallel, incubate identical vials in an...

Research

JoVE Journal - Biology
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Isothermal Titration Calorimetry for Measuring Macromolecule-Ligand Affinity

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Cited by 84 •

2011

A general protocol for the use of isothermal titration calorimetry to monitor the binding thermodynamics for biological systems with moderate binding affinities is presented.

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