Metal Edta Complex

A metal-EDTA complex is a coordination compound in which ethylenediaminetetraacetic acid (EDTA) binds a metal ion through multiple donor atoms, forming a stable chelate. In aqueous solution, EDTA can wrap around the metal center through its nitrogen and oxygen atoms, with complex formation influenced by pH, metal-ion identity, and the relative concentrations of reactants. These complexes are important in analytical chemistry, where EDTA titrations determine metal-ion concentrations and water hardness, and in chemical separations and formulations, where EDTA controls the availability and reactivity of metal ions. Their stability also supports studies of coordination chemistry and metal speciation.

Metal Edta Complex - Related Videos

Education

JoVE Core - Analytical Chemistry

EDTA: Auxiliary Complexing Reagents

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2024

EDTA titrations are usually carried out in highly basic conditions, where the fully deprotonated form of EDTA, Y4−, actively complexes with the free metal ions in the solution. Several metal ions precipitate as hydrous oxide (hydroxides, oxides, or oxyhydroxides) under these conditions, lowering the concentration of free metal ions in the solution. For this reason, auxiliary complexing agents or ligands such as ammonia, tartrate, citrate, or triethanolamine are used in EDTA titrations to...

Research

JoVE Journal - Chemistry

Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay

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Cited by 64 •

2013

A method for synthesis of air-sensitive titanium and vanadium anticancer agents is described, along with the evaluation of their cytotoxic activity towards human cancer cell line by the MTT Assay.

Synthesis of a Water-soluble Metal–Organic Complex Array

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Cited by 1 •

2016

A potential general method for the synthesis of water-soluble multimetallic peptidic arrays containing a predetermined sequence of metal centers is presented.

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

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Cited by 4 •

2013

The NMR-solution structure of a metallochaperone model peptide with Cu (I) was determined, and a detailed protocol from sample preparation and 1D and 2D data collection to a three-dimensional structure is described.

Metal-Ligand Bonds

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2020

The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes. In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...

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