In Situ Simulation
In Situ Simulation - Related Videos
08:00
Whole-Mount In Situ Hybridization
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2023
Whole-mount in situ hybridization (WMISH) is a common technique used for visualizing the location of expressed RNAs in embryos. In this process, synthetically produced RNA probes are first complementarily bound, or "hybridized," to the transcripts of target genes. Immunohistochemistry or fluorescence is then used to detect these RNA hybrids, revealing spatial and temporal patterns of gene expression. Unlike traditional in situ hybridization techniques, which require thin tissue sections whose...
14:33
Optimize Flue Gas Settings to Promote Microalgae Growth in Photobioreactors via Computer Simulations
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Cited by 5 •
2013
Flue gas from power plants is a cheap CO2 source for algal growth. We have built prototype "flue gas to algal cultivation" systems and described how to scale up the algal cultivation process. We have demonstrated the use of a mass-transfer bio-reaction model to simulate and to design the optimal operation of flue gas for the growth of Chlorella sp. in algal photo-bioreactors.
07:56
A Set of In Situ Informed Simulated Medium Formats for Culturing Environmentally Acquired Anaerobic Microorganisms
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2024
The focus of this paper is to detail best practices for making media for fastidious anaerobic microorganisms acquired from an environment. These methods help manage anaerobic cultures and can be applied to support the growth of elusive uncultured microorganisms, the "microbial dark...
09:46
MPI CyberMotion Simulator: Implementation of a Novel Motion Simulator to Investigate Multisensory Path Integration in Three Dimensions
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Cited by 48 •
2012
An efficient way to gain insight into how humans navigate themselves in three dimensions is described. The method takes advantage of a motion simulator capable of moving observers in ways unattainable by traditional simulators. Results confirm that movement in the horizontal plane is underestimated, while vertical movement is overestimated.
08:45
Study of Siphon Breaker Experiment and Simulation for a Research Reactor
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Cited by 2 •
2017
The siphon breaking phenomenon was investigated experimentally and a theoretical model was proposed. A simulation program based on the theoretical model was developed and the results of the simulation program were compared with experimental results. It was concluded that the results of the simulation program matched the experimental results well.
FAQs
By placing a scenario in the working environment, the method exposes how actual layouts, available equipment, procedures, communication demands, and unexpected constraints interact. These conditions can reveal latent safety hazards, meaning risks embedded in the system rather than obvious individual errors. The findings help teams identify weaknesses in workflows and improve the resilience of operations.
Observation captures how people, systems, and equipment function during the scenario, including responses to procedures and communication demands. A structured debriefing then examines what occurred and why, giving participants and facilitators a basis for identifying hazards, coordination problems, and improvement opportunities. Together, these elements turn a practice event into information for workflow and competency development.
The main distinction is the setting and the constraints it preserves. A dedicated center can support controlled practice, whereas In Situ Simulation examines performance where the work actually occurs, with the relevant layout, equipment placement, and coordination demands present. This comparison matters when researchers need to assess whether procedures remain workable under authentic environmental conditions.
A typical exercise selects a realistic event, places it in the environment where work occurs, and prepares trained facilitators to guide the scenario. Participants then respond while observers examine procedures, communication, equipment use, and unexpected constraints. Afterward, a structured debriefing reviews the response and translates observed hazards or gaps into workflow, competency, or system improvements.
The approach can be used in laboratories, industrial sites, remote locations, and other operational environments relevant to the work being assessed. In these settings, teams can examine emergency preparedness, field protocols, equipment placement, and coordination without separating the exercise from its environmental context. This makes the method relevant to both environmental research and practical operations.
Results can show whether emergency procedures, field protocols, equipment arrangements, and coordination practices function effectively under realistic conditions. The exercise may also expose latent safety hazards that are difficult to identify away from the workplace. Researchers and operational teams can use these findings to guide workflow improvements, competency development, and more resilient systems.