Corneal Flap

A corneal flap is a thin, hinged layer of the cornea created to provide access to the underlying stromal tissue during refractive eye surgery, particularly LASIK. A microkeratome or femtosecond laser separates the flap along a precise plane while preserving its attachment, allowing surgeons to lift it, reshape the exposed cornea with an excimer laser, and then reposition the flap without sutures. This process changes corneal curvature to improve the eye’s focusing power and correct refractive errors such as myopia, hyperopia, and astigmatism. Understanding flap creation and healing is essential for surgical planning, patient safety, and evaluating outcomes in ophthalmic medicine.

Corneal Flap - Related Videos

Research

JoVE Journal - Bioengineering

Engineered Vascularized Muscle Flap

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Cited by 6 •

2016

To date, thick tissue defects are typically reconstructed by applying autologous tissue flaps or engineered tissues. In this protocol, we present a new method for engineering vascularized tissue flap bearing an autologous pedicle, to serve as a substitute to autologous flaps.

Research

JoVE Journal - Medicine

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

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2025

This protocol describes the surgical technique for harvesting a human perforator flap model based on the deep inferior epigastric artery pedicle, intended for experimental research.

Research

JoVE Journal - Medicine
Free Sample

A Model of Free Tissue Transfer: The Rat Epigastric Free Flap

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Cited by 22 •

2017

This paper describes the steps required to raise a fasciocutaneous epigastric free flap and transfer it to the neck in the rat.

Research

JoVE Journal - Medicine
Free Sample

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

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Cited by 31 •

2012

Endothelial corneal transplantation is a surgical technique for treatment of posterior corneal diseases. Mechanical microkeratome dissection to prepare tissue results in thinner, more symmetric grafts with less endothelial cell loss and improved outcomes. Dissections can be performed at the eye bank prior to corneal transplantation surgery.

An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse

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Cited by 83 •

2014

Neovascularization (NV) of the cornea can complicate multiple visual pathologies. Utilizing a controlled, alkali-burn injury model, a quantifiable level of corneal NV can be produced for mechanistic study of corneal NV and evaluation of potential therapies for neovascular disorders.

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