Gastric Reflux
Gastric Reflux - Related Videos
05:19
Surgical Models of Gastroesophageal Reflux with Mice
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Cited by 8 •
2015
This article demonstrates surgical procedures of gastroesophageal reflux with mice. These models are useful tools for research on mechanisms and treatment of gastroesophageal reflux disease and potentially Barrett’s esophagus and esophageal adenocarcinoma.
11:20
The Effect of Reflux Ratio on Tray Distillation Efficiency
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2023
Source: Kerry M. Dooley and Michael G. Benton, Department of Chemical Engineering, Louisiana State University, Baton Rouge, LA Tray and packed columns are both commonly used for distillation, absorption, and stripping separation operations.1,2 The goal of this experiment is to distill a mixture of alcohols (methanol, isopropanol) and water in a sieve tray column and examine how closely simple theories of distillation based on equilibrium assumptions are followed. Sieve trays provide maximum...
07:55
Assembly of a Reflux System for Heated Chemical Reactions
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2023
Source: Laboratory of Dr. Philip Miller — Imperial College London Many chemical experiments require elevated temperatures before any reaction is observed, however heating solutions of reactants can lead to loss of reactants and/or solvent via evaporation if their boiling points are sufficiently low. In order to ensure no loss of reactants or solvent, a reflux system is used in order to condense any vapors produced on heating and return these condensates to the reaction...
01:25
Gastroesophageal Reflux Disease
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2026
Gastroesophageal reflux disease (GERD) is the backward flow of stomach contents (acid, pepsin, or bile) into the esophagus, causing mucosal inflammation known as esophagitis. It results from failure of antireflux mechanisms, mainly the lower esophageal sphincter (LES), influenced by mechanical and physiological factors.Etiology and Risk FactorsGERD develops when LES function is weakened or when intra-abdominal pressure increases. Risk factors include aging, obesity, and sliding hiatal hernia,...
05:18
Roux-en-Y Gastric Bypass Procedure: A Bariatric Surgical Procedure for Gastric Resectioning in Murine Model
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2025
This video describes a bariatric surgery-Roux-en-Y procedure. This involves the cutting of the jejunum- the middle portion of the intestine- to generate two intestinal limbs. The biliary limb is attached to the existing intestinal loop and the alimentary limb is attached to the stomach, creating a gastric bypass. The gastric bypass created here helps to decrease the nutrient uptake and efficiently reduces body weight.
FAQs
The lower esophageal sphincter normally contributes to the barrier separating the stomach from the esophagus. When it relaxes inappropriately or becomes weaker, that barrier is less effective, making upward movement more likely. This mechanism explains why changes in sphincter function are central to understanding symptoms and why some treatments aim to restore the separation between the two organs.
Reflux may become more noticeable after meals because the stomach contains recently consumed food and gastric fluid that can move upward when the barrier is ineffective. Lying down is also identified as a setting in which reflux can occur. These patterns help connect symptoms with daily circumstances during clinical assessment and management.
A single or occasional episode can represent a common digestive process, whereas recurrent reflux may affect esophageal health. When reflux persists and produces ongoing consequences such as discomfort or inflammation, it can develop into gastroesophageal reflux disease. This distinction matters because persistent symptoms warrant greater clinical attention than isolated episodes.
The material moving upward may include acidic gastric fluid and partially digested food. Contact with this material can produce discomfort, regurgitation, or inflammation, and repeated exposure may affect esophageal health. The range of possible effects explains why clinicians consider both the immediate symptoms and the longer-term consequences when evaluating recurrent reflux.
Management may begin with lifestyle changes and can include acid-reducing medicines. These approaches address reflux-related symptoms and the effects of acidic gastric contents, although the appropriate strategy depends on the clinical situation. Because persistent reflux may affect esophageal health, treatment is considered alongside clinical assessment rather than based only on an isolated episode.
Procedures may be considered in selected cases, particularly when restoring the barrier between the stomach and esophagus is an important treatment goal. This approach differs from acid-reducing medicines, which target the acidic component of gastric contents. The procedural option therefore represents a distinct management pathway within clinical care for persistent or consequential reflux.