Inducible System
Inducible System - Related Videos
09:23
Lateral Root Inducible System in Arabidopsis and Maize
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Cited by 8 •
2016
The Lateral Root Inducible System (LRIS) allows for synchronous induction of lateral roots and is presented for Arabidopsis thaliana and maize.
08:58
Induced Pluripotency
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2023
Induced pluripotent stem cells (iPSCs) are somatic cells that have been genetically reprogrammed to form undifferentiated stem cells. Like embryonic stem cells, iPSCs can be grown in culture conditions that promote differentiation into different cell types. Thus, iPSCs may provide a potentially unlimited source of any human cell type, which is a major breakthrough in the field of regenerative medicine. However, more research into the derivation and differentiation of iPSCs is still needed to...
10:22
Inducing Emotions
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2023
Source: William Brady & Jay Van Bavel—New York University Psychologists have long known that people behave differently in good moods versus bad moods, and this general principle extends to consumer behavior. Economists, as well, have come to appreciate that an individual’s financial decisions are not solely the result of extensive cost-benefit calculations; other factors like emotion are at play. Further, incidental emotions affect the behavior of buyers and sellers even though they are...
06:03
Motion-induced Blindness
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2023
Source: Laboratory of Jonathan Flombaum—Johns Hopkins University One thing becomes very salient after basic exposure to the science of visual perception and sensation: what people see is a creation of the brain. As a result people may fail to see things, see things that are not there, or see things in a distorted way. To distinguish between physical reality and what people perceive, scientists use the term awareness to refer to what people perceive. To study awareness, vision scientists often...
05:44
Research Application of Laser-Induced Shock Wave for Studying Blast-Induced Cochlear Injury
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2024
Here, we describe experimental protocols for creating an animal model of blast-induced cochlear injury using laser-induced shock wave (LISW). Exposure of the temporal bone to LISW allows the reproduction of blast-induced cochlear pathophysiology. This animal model could be a platform for elucidating cochlear pathology and exploring potential treatments for blast injuries.
FAQs
An inducible system translates a chosen signal through a regulatory switch that activates a promoter, receptor, or signaling pathway. That activated control point initiates expression of a target gene or production of a therapeutic factor. The particular switch therefore determines how the external or internal cue is connected to the desired biological response.
Reversibility allows activity to fall when the inducing stimulus is removed, which helps separate the effects of turning a process on from its baseline state. This feature is valuable when researchers need temporal control, want to reduce prolonged activity, or must examine how a regulated process changes after induction ends.
Control over when and where activity occurs is important because the same target gene or therapeutic factor may produce different consequences depending on its timing and location. By tuning induction rather than treating activity as permanently present, investigators can improve experimental precision and seek stronger control over unwanted effects in biomedical models.
Researchers first identify the signal that should control the process and then link it to an appropriate regulatory switch, such as a promoter, receptor, or signaling pathway. They expose the biological or engineered system to the defined cue, measure target activity or factor production, and, where reversibility is available, assess the response after stimulus removal.
These systems are useful when a study requires a controlled change rather than continuous activity. In disease modeling, induction can help initiate a selected biological process at a chosen stage. In drug screening, it can provide a controllable target response, making it easier to examine how candidate interventions perform under defined experimental conditions.
In therapeutic research, controlled production of a therapeutic factor can help limit unwanted effects by restricting activity to an intended time or location. The same principle supports development of cell- and gene-based treatments in which researchers seek tunable regulation rather than unrestrained activity. This makes induction relevant to treatment design as well as laboratory control.