Organ Implantation

Organ implantation is the surgical placement of a donor organ or engineered organ into a recipient’s body to replace or support a failing organ and restore physiological function. During the procedure, surgeons position the organ, connect its blood vessels and, when necessary, other ducts or tissues, while clinicians manage ischemia, reperfusion, and immune compatibility. In medicine, organ implantation supports transplantation of organs such as kidneys, livers, hearts, and lungs, and advances in tissue engineering may expand its use with bioengineered grafts. Outcomes depend on surgical technique, organ function, rejection prevention, and long-term monitoring of the recipient.

Organ Implantation - Related Videos

Research

JoVE Journal - Neuroscience

A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals

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Cited by 7 •

2014

Implanting organized arrays of microwires for use in single-unit electrophysiological recordings presents a number of technical challenges. Methods for performing this technique and the equipment necessary are described. Also, the beneficial use of organized microwire arrays to record from distinct neural subregions with high spatial selectivity is discussed.

Ultrasound-Guided Implantation: A Technique to Implant Pancreatic Ductal Adenocarcinoma Cells into an Adult Mouse

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2023

This video describes the protocol for ultrasound-guided orthotopic implantation of murine-derived pancreatic ductal adenocarcinoma cells directly into the pancreas of the mouse. This causes less inflammation at the implantation site compared to surgical procedures.

Implantation of Engineered Tissue in the Rat Heart

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Cited by 4 •

2009

Here, we describe a cardiac surgical procedure to implant engineered tissue in the atrioventricular (AV)-groove of an adult Lewis rat.

Research

JoVE Journal - Medicine
Free Sample

Implantation of the Syncardia Total Artificial Heart

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Cited by 12 •

2014

The purpose of this manuscript is to briefly review indications, management, and outcomes for the total artificial heart. Video operative techniques for device implantation are presented.

Microbead Implantation in the Zebrafish Embryo

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Cited by 8 •

2015

The zebrafish is an excellent model system for genetic and developmental studies. Bead implantation is a valuable tissue manipulation technique that can be used to interrogate developmental mechanisms by introducing alterations in local cellular environments. This protocol describes how to perform microbead implantation in the zebrafish embryo.

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