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A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals
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Neuroscience
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JoVE Journal Neuroscience
A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals

A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals

DOI:
10.3791/51004-v

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10:58 min

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February 14, 2014

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, , , ,
1Department of Psychology,Rutgers, the State University of New Jersey, 2Neuronal Networks Section, Integrative Neuroscience Research Branch,National Institute on Drug Abuse

Chapters

  • 00:05Title
  • 01:58Preparing the Animal for Surgery
  • 03:05Performing the Craniotomy
  • 06:00Implanting the Microwire Array
  • 08:54Suturing and Post-operative Animal Care
  • 09:30Neural Discharge Measured by the Microwire Array
  • 10:11Conclusion

Summary

Automatic Translation

Automatic Translation

Implanting organized arrays of microwires for use in single-unit electrophysiological recordings presents a number of technical challenges. Methods for performing this technique and the equipment necessary are described. Also, the beneficial use of organized microwire arrays to record from distinct neural subregions with high spatial selectivity is discussed.

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Keywords: Single-unit RecordingsMicrowire ImplantationAwake Behaving AnimalsIn Vivo ElectrophysiologyNeural SignalingChronic ImplantationElectrode TrackingImmunohistochemistry

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