Tactile Pain Threshold

Tactile pain threshold is the minimum intensity of a touch or pressure stimulus that a person identifies as painful, providing a psychophysical measure of nociceptive sensitivity. During testing, calibrated mechanical stimuli are applied in gradually increasing or standardized steps until the participant reports pain; mechanosensitive nociceptors then transmit signals through peripheral nerves and spinal pathways to the brain, where the sensation is interpreted. Measuring this threshold helps characterize sensory function, detect altered pain sensitivity in conditions such as peripheral neuropathy, and evaluate changes associated with injury, disease, or analgesic treatment. Results can support clinical assessment and pain research.

Tactile Pain Threshold - Related Videos

Research

JoVE Journal - Behavior

Measurement of Vibration Detection Threshold and Tactile Spatial Acuity in Human Subjects

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Cited by 9 •

2016

Here, we present protocols to determine vibration detection thresholds and tactile acuity using psychophysical methods in man.

Research

JoVE Journal - Behavior
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Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

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Cited by 17 •

2016

Human pain models are valuable tools used to assess the analgesic potential of novel compounds and predict their clinical efficacy, especially when used in an integrated manner. Although implementation of these models is complex, with proper execution, the pain models described in this protocol can provide predictive and reliable results.

Research

JoVE Journal - Biology
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Determining heat and mechanical pain threshold in inflamed skin of human subjects

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Cited by 21 •

2009

Algorithms assessing heat and mechanical pain thresholds in experimentally inflamed skin of human study subjects are shown. The two pain testing paradigms independently examine nociceptive processing by the two major peripheral nerve fiber populations transmitting pain, i.e., non-myelinated C fibers and small myelinated A-delta fibers.

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

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Cited by 8 •

2017

Psychophysical methods such as the QUEST estimation procedure can efficiently yield robust estimates of the stimulation intensity at which nonpainful sensations transition into painful sensations. By stimulating repeatedly at the threshold intensity, the variability in rating responses can directly be attributed to perceptual classifications in subsequent analyses.

Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats

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Cited by 55 •

2012

We describe two tactile sensory testing methods for acute or chronic periods of spinal cord injury in rats. These validated procedures can detect the development and maintenance of allodynia-like sensations.

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