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Determining heat and mechanical pain threshold in inflamed skin of human subjects
JoVE Journal
Biology
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JoVE Journal Biology
Determining heat and mechanical pain threshold in inflamed skin of human subjects
DOI:

13:21 min

January 14, 2009

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Chapters

  • 00:00Title
  • 01:05Introduction
  • 02:06Heat Pain Testing Using the TSA II
  • 03:02Preparation and Training the Subjects
  • 08:08Determining the Pain Threshold
  • 10:04Mechanical Pain Testing with Punctuated Pressure Probes
  • 11:01Determining the Mechanical Pain Threshold
  • 12:42Conclusion

Summary

Automatic Translation

Algorithms assessing heat and mechanical pain thresholds in experimentally inflamed skin of human study subjects are shown. The two pain testing paradigms independently examine nociceptive processing by the two major peripheral nerve fiber populations transmitting pain, i.e., non-myelinated C fibers and small myelinated A-delta fibers.

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