JoVE Encyclopedie van Experimenten
Neurowetenschap
0 weergaven • 3:15 min. • August 29th, 2025
Begin with a patient diagnosed with post-traumatic stress disorder, or PTSD.
This disorder causes reduced activity in the medial prefrontal cortex, or mPFC, thereby preventing inhibition of the amygdala.
As a result, the amygdala, a fear-processing center, becomes overactive, leading to heightened and persistent fear responses.
Using the guide cap on the patient’s head, position the deep transcranial magnetic stimulation, or dTMS, helmet over the right motor cortex.
The helmet contains a magnetic coil wound in multiple planes, which generates a magnetic field that penetrates deeper brain regions to activate target areas effectively.
Apply minimum intensity pulses to the motor cortex to trigger hand muscle contraction.
Reposition the helmet over the mPFC and deliver suprathreshold pulses to stimulate neural activity.
Increasing mPFC activation restores its inhibitory control over the amygdala, thereby reducing fear responses and alleviating PTSD symptoms.
Begin by placing the blue cap with the two intercepting rulers, on to the subject. Then place the zero cm mark of the white sagittal ruler on the nasion. And the 25 cm mark of the clear coronal ruler, at 40%of the nasion-inion distance, wi
Bekijk het volledige transcript en krijg toegang tot duizenden wetenschappelijke video's