Neurostimulation System Setup and Symptom Collection for Personalized Treatment of Depression

Begin with a patient diagnosed with depression, implanted with an implantable neurostimulator or INS.

The INS uses cortical and depth electrodes to record brain activity through electrocorticography, detecting abnormal patterns linked to depression.

Connect a telemetry wand to the programmer and position it over the INS for wireless communication.

Log into the patient’s data-management system.

Adjust the electrocorticography recording settings.

Swipe a magnet over the INS to trigger the first recording.

The patient then completes a symptom survey, documenting his emotional state.

Once the survey is complete, swipe the magnet again to trigger a second recording, capturing

brain activity changes during symptom reporting.

Place the wand over the INS to transfer data from both recordings to the system.

Doctors analyze the recordings and symptom reports to identify a personalized biomarker—a unique brain activity pattern linked to symptom severity.

The INS delivers closed-loop neurostimulation only when this biomarker is detected.

To begin, ensure the patient has fully recovered from surgery following the implantation of the device with cortical in-depth leads. Connect the telemetry wand to the pr