Core Shell Nanoparticles
Core Shell Nanoparticles - Related Videos
08:19
Synthesis, Characterization, and Functionalization of Hybrid Au/CdS and Au/ZnS Core/Shell Nanoparticles
0 Views •
Cited by 3 •
2016
The synthesis of uniform gold nanoparticles coated with semiconductor shells of CdS or ZnS is performed. The semiconductor coating is conducted by first depositing a silver sulfide shell and exchanging the silver cations for zinc or cadmium cations.
08:12
Generation of Zerovalent Metal Core Nanoparticles Using n-(2-aminoethyl)-3-aminosilanetriol
0 Views •
Cited by 4 •
2016
A novel method for metal core nanoparticle synthesis using a water stable silanol is described.
02:10
The Nucleosome Core Particle
0 Views •
2020
Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins. The paradox Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
02:29
Intravenous Administration of Therapeutic Nanoparticles in a Murine Glioblastoma Model
0 Views •
2025
Source: Kim, B. D., et al. Nanoparticle Delivery of an Oligonucleotide Payload in a Glioblastoma Multiforme Animal Model. J. Vis. Exp. (2024)This video demonstrates the intravenous injection of therapeutic nanoparticles in a glioblastoma-bearing mouse. The method enables targeted delivery across the blood-brain barrier and supports non-invasive imaging for evaluating nanoparticle biodistribution and therapeutic efficacy in brain tumors.
02:23
Visualizing the Effect of pH on Solubilization of the Influenza A Viral Core
0 Views •
2026
Source: Stauffer, S. et al., In Vitro Disassembly of Influenza A Virus Capsids by Gradient Centrifugation. J. Vis. Exp. (2016)This video demonstrates the effect of pH on the solubilization of influenza A viral cores. Gel electrophoresis and protein staining reveal the progressive disassembly of the core structure under acidic conditions.
FAQs
Composition determines which chemical, optical, or magnetic properties each region contributes, while thickness changes how strongly the core and shell influence one another. The interface is especially important because it connects these regions and can alter overall behavior. By adjusting all three factors, researchers can combine functional roles while controlling how the particle responds to its environment.
Shell thickness helps determine how effectively the outer region controls exposure of the core to surrounding materials. A shell can modify surface reactivity and improve chemical stability, while changes in thickness can shift the balance between protection and access to core-related properties. This makes thickness an important design variable for catalysis, sensing, and controlled delivery applications.
The core and shell can be selected or tuned so that different regions contribute distinct optical or magnetic responses within one nanoscale structure. Their composition, morphology, and interface then influence how those responses are expressed together. This separation of functional roles supports designs for imaging, sensing, and other materials research where multiple properties must operate in the same particle.
The interface provides a chemically and physically important boundary between the core and shell. Its composition and structure can affect surface reactivity, chemical stability, and interactions with nearby substances. Consequently, interface control helps determine whether a particle remains protected, participates in chemical processes, or responds selectively to its surroundings, making it central to performance optimization.
A practical design strategy considers particle size, morphology, composition, shell thickness, and the properties of the core-shell interface. These variables should be adjusted according to the intended function, such as reactivity, optical response, magnetic behavior, stability, or interaction with surrounding materials. Coordinating them allows researchers to target a specific performance profile rather than relying on one material property alone.
They are useful when a single nanoscale material must provide separated but coordinated functions. Chemistry researchers apply them in catalysis and sensing to control interactions and reactivity, and in imaging or energy conversion to exploit optical or other responses. Their tunable structures also support controlled delivery, where composition and shell design can help regulate interactions with the surrounding environment.