Intermittent Claudication
Intermittent Claudication - Related Videos
14:52
Computerized Dynamic Posturography for Postural Control Assessment in Patients with Intermittent Claudication
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Cited by 57 •
2013
Individuals with intermittent claudication exhibit poor balance compared to healthy controls. Computerized dynamic posturography is an objective method for measuring an individual's postural responses to balance disturbances. This provides an objective reflection of the person’s ability to respond to situations under which sensory stimuli are altered and unexpected perturbations occur.
09:26
Preparing and Administering Secondary Intermittent Intravenous Medications
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2017
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT Secondary intravenous (IV) infusions are a way to administer smaller volume-controlled amounts of IV solution (25-250 mL). Secondary IV infusions are delivered over longer periods of time than IV push medications, which reduces the risks associated with rapid infusions, such as phlebitis and infiltration. In addition, some antibiotic medications are only stable for a limited time in...
05:15
Intermittent Binge-Intake Model in Mice
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2025
A binge-eating model was established in mice using intermittent access to M&M's (a highly palatable food made of fat and sugar). Mice with intermittent access to this high-fat, high-sugar food showed stress-like behaviors, increased caloric intake, and a preference for that food over standard chow compared to mice with continuous or no access to the food.
05:45
Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures
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Cited by 1 •
2015
This article describes the methodology for administering short periods of intermittent hypoxia to postnatal day 1-8 mouse or rat pups. This approach effectively elicits a robust tissue level “priming effect” on cultured neural progenitor cells that are harvested within 30 min of hypoxia exposure.
01:24
Drug Accumulation During Multiple Dosing: Intermittent IV Infusions
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2025
Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
FAQs
The key physiological issue is an oxygen supply-demand mismatch in active leg muscle. Walking increases the muscles’ need for oxygen, but narrowed peripheral arteries cannot provide enough additional blood flow. The resulting imbalance produces symptoms during exertion, while stopping reduces muscle demand and allows symptoms to improve. This pattern helps clinicians connect complaints with vascular limitation.
The reproducible relationship between activity and symptom relief provides an important clinical clue rather than an isolated description of leg discomfort. Clinicians can use the pattern together with physical examination findings to assess whether reduced circulation may be contributing to the patient’s complaints. This supports recognition of peripheral artery disease and guides decisions about confirmatory testing.
The ankle-brachial index is a circulation test used to evaluate possible lower-extremity arterial disease. It complements the reported symptom pattern and physical examination, giving clinicians an additional way to assess impaired blood flow. Its findings can support identification of underlying vascular disease and contribute to treatment planning, including decisions about exercise therapy, medication, or further procedures.
No single clinical element provides the entire assessment. The symptom pattern identifies an exertional concern, physical examination adds information about circulation, and tests such as the ankle-brachial index help evaluate arterial blood flow. Combining these sources allows clinicians to move from recognizing a complaint to identifying underlying vascular disease and selecting an appropriate management strategy.
Evaluation begins by characterizing the patient’s walking-related pain, cramping, or fatigue and whether it improves with rest. Clinicians then perform a physical examination focused on circulation and may use tests such as the ankle-brachial index. Together, these steps help assess peripheral arterial disease, establish the vascular context, and inform decisions about treatment and follow-up.
The clinical findings help determine whether management should emphasize exercise therapy, medication, or procedures intended to improve blood flow. Treatment planning addresses both the patient’s exertional symptoms and the underlying vascular disease. The selected approach depends on the assessment, while ongoing cardiovascular risk management remains important for reducing the likelihood of disease progression.
Recognizing the symptom pattern can reveal underlying peripheral artery disease and prompt broader cardiovascular risk management. This matters because the clinical goal extends beyond reducing walking-related discomfort: clinicians also aim to address vascular disease and limit its progression. Early recognition therefore supports a more complete care plan that combines assessment, risk management, and appropriate treatment.