Droplet Trapping
Droplet Trapping - Related Videos
06:38
Droplet Digital TRAP (ddTRAP): Adaptation of the Telomere Repeat Amplification Protocol to Droplet Digital Polymerase Chain Reaction
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Cited by 4 •
2019
We successfully converted the standard telomere repeat amplification protocol (TRAP) assay to be employed in droplet digital polymerase chain reactions. This new assay, called ddTRAP, is more sensitive and quantitative, allowing for better detection and statistical analysis of telomerase activity within various human cells.
01:41
Social Traps
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2020
Social traps are negative situations where people get caught in a direction or relationship that later proves to be unpleasant, with no easy way to back out of or avoid. The concept was orignally introduced by John Platt who applied psychology to Garrett Hardin's "Tragedy of the Commons", where in New England herd owners could let their cattle graze in the common ground. This situation seems like a good idea, but an individual could have an advantage. If they owned more cows, the larger...
11:45
Experimental Methods for Trapping Ions Using Microfabricated Surface Ion Traps
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Cited by 19 •
2017
This paper presents a microfabrication methodology for surface ion traps, as well as a detailed experimental procedure for trapping ytterbium ions in a room-temperature environment.
13:39
Optical Trapping of Nanoparticles
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Cited by 7 •
2013
The following setup approach details low power optical trapping of dielectric nanoparticles using a double-nanohole in metal film.
05:57
Dean-Stark Trap
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2023
Source: Vy M. Dong and Jan Riedel, Department of Chemistry, University of California, Irvine, CA A Dean-Stark trap is a special piece of glassware, which allows the collection of water during a reaction through an azeotropic distillation. The desire to collect water from a reaction can have various reasons. It can drive the equilibria in reactions, where water is formed as a byproduct. According to Le Chatelier's principle, a change in temperature, pressure, concentration, or volume will cause...
FAQs
Trap geometry creates a preferred path in which a droplet enters a cavity or chamber rather than continuing with the surrounding continuous phase. The dimensions and arrangement of these features work with flow resistance and interfacial tension to promote capture at defined sites. Engineering the geometry therefore determines where droplets are positioned and supports consistent downstream observation or manipulation.
Flow resistance redistributes the moving phases around a trap, while interfacial tension influences whether a droplet deforms, enters, or remains outside a cavity. Their combined effects help distinguish the droplet pathway from the continuous-phase pathway. Controlling these factors is important because capture depends on the balance between droplet motion, deformation, and retention within the device.
Pressure and flow conditions help keep the droplet retained after it reaches the trapping site. If the operating conditions do not support sufficient retention, the droplet may not remain positioned for controlled processing or observation. Adjusting these conditions allows an engineering system to preserve discrete reaction volumes while the surrounding continuous phase continues to pass through the microfluidic device.
A typical workflow establishes trapping locations, directs droplets through the device, and uses the local geometry and flow behavior to move selected droplets into cavities or chambers. Pressure and flow are then maintained to support retention. Once held, the droplets can be manipulated or monitored over time, allowing controlled work with small reaction volumes at defined positions.
Trapped droplets can support parallel chemical reactions, biological assays, and material synthesis within a microfluidic platform. They also enable researchers to observe droplet behavior over time rather than relying only on measurements during transit. These uses make the approach relevant when experiments require localized processing, repeated comparison among droplets, or controlled handling of limited sample and reagent volumes.
The method gives engineers greater control over droplet position, processing, and measurement inside compact lab-on-a-chip systems. Holding many droplets at defined locations can support parallel operation and increase experimental throughput while reducing sample and reagent use. In engineering research, this combination is valuable for designing systems that integrate reaction control, observation, and small-volume experimentation.