Clearance Filtration Measurement

Clearance Filtration Measurement is the quantitative assessment of how effectively a filtration system removes suspended particles, microorganisms, or dissolved contaminants from a fluid. It works by comparing contaminant concentrations before and after treatment under defined flow, pressure, and filter conditions, with the difference indicating removal performance or clearance efficiency. In environmental science, these measurements help characterize water and air treatment systems, evaluate filter capacity, and identify performance changes caused by loading or fouling. Standardized clearance data support process optimization, regulatory monitoring, and decisions about filter replacement, while providing a basis for comparing filtration materials and operating conditions.

Clearance Filtration Measurement - Related Videos

Research

JoVE Journal - Biology
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A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice

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Cited by 65 •

2013

Measurement of glomerular filtration rate (GFR) is the gold standard for kidney function assessment. Here we describe a high-throughput method which allows the determination of GFR in conscious mice by using a single bolus injection, determination of fluorescein isothiocyanate (FITC)-inulin in plasma and calculation of GFR by a two-phase exponential decay model.

Research

JoVE Journal - Behavior
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Quantifying Food Intake in Caenorhabditis elegans by Measuring Bacterial Clearance

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Cited by 4 •

2024

This protocol describes an assay to quantify Caenorhabditis elegans feeding rate based on measuring the clearance of bacteria in liquid culture.

Research

JoVE Journal - Medicine
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Transdermal Measurement of Glomerular Filtration Rate in Mice

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Cited by 101 •

2018

Here we describe a protocol to measure glomerular filtration rate (GFR) in conscious, freely moving mice using a transdermal GFR monitor.

Education

JoVE Core - Biology

Filtration and Urine Formation

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2019

The function of the kidneys is to filter, reabsorb, secrete, and excrete. Every day the kidneys filter nearly 180 liters of blood, initially removing water and solutes but ultimately returning nearly all filtrates into circulation with the help of osmoregulatory hormones. This process removes wastes and toxins but is also crucial to maintain water and electrolyte levels. Most of these functions are performed by the tiny but numerous nephrons contained within the kidneys. Blood enters the renal...

Glomerular Filtration: Net Filtration Pressure

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2025

Glomerular filtration, a key process in the kidneys, is regulated by three main pressures: Glomerular blood hydrostatic pressure (GBHP), Capsular hydrostatic pressure (CHP), and Blood colloid osmotic pressure (BCOP). GBHP, with an average value of 55 mmHg, promotes filtration by pushing water and solutes through the filtration membrane. This is balanced by two opposing forces: CHP, a "back pressure" exerted against the filtration membrane by fluid already in the capsular space and renal tubule,...

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