Cognitive Fusion Biopsy

Cognitive fusion biopsy is a targeted biopsy method in which clinicians use their mental interpretation of preprocedural magnetic resonance imaging (MRI) to guide tissue sampling during real-time ultrasound, most commonly for suspected prostate cancer. The operator mentally aligns the location and appearance of MRI-visible lesions with the prostate anatomy on ultrasound, then directs the needle toward those regions while obtaining biopsy cores. This approach can complement systematic sampling and may improve detection of clinically significant tumors compared with unguided biopsy alone. It is especially useful when dedicated software-fusion or in-bore MRI biopsy is unavailable, although its accuracy depends on imaging quality, anatomical correspondence, and operator experience.

Cognitive Fusion Biopsy - Related Videos

Research

JoVE Journal - Medicine

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound

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Cited by 2 •

2025

Prostate biopsy is the gold standard diagnostic method for prostate cancer. Cognitive fusion-guided prostate biopsy, which combines transrectal ultrasound with pre-measured MRI parameters, improves biopsy accuracy and enhances the detection rate of clinically significant prostate cancer.

Research

JoVE Journal - Medicine
Free Sample

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

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Cited by 4 •

2019

Presented herein is a protocol to perform targeted biopsy of the prostate using an MRI-ultrasound fusion system.

Education

JoVE Core - Chemistry

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2020

The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons. A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...

An Introduction to Cognition

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2023

Cognition encompasses mental processes such as memory, perception, decision-making reasoning and language. Cognitive scientists are using a combination of behavioral and neuropsychological techniques to investigate the underlying neural substrates of cognition. They are interested in understanding how information is perceived, processed and how does it affect the final execution of behaviors. With this knowledge, researchers hope to develop new treatments for individuals with cognitive...

Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance

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2025

This protocol presents a more precise and effective method of repetitive transcranial magnetic stimulation of the dorsolateral and dorsomedial prefrontal cortices during an experimental task using neuronavigation and robotic systems. Based on the results, crucial implications are suggested for future online stimulation research.

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