Glisson's Capsule

Glisson's capsule is a fibroelastic connective tissue layer that surrounds the liver and helps maintain its structural integrity. It is continuous with connective tissue around the portal triads and sends delicate extensions into the hepatic parenchyma, providing support for branches of the portal vein, hepatic artery, bile ducts, lymphatic vessels, and nerves. Sensory fibers within the capsule can transmit pain when the liver enlarges or the capsule becomes stretched, making it clinically relevant in hepatitis, congestion, and tumors. Understanding its anatomy supports interpretation of liver imaging, assessment of hepatobiliary pain, and planning for liver surgery and biopsy.

Glisson's Capsule - Related Videos

Research

JoVE Journal - Medicine
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Teratoma Generation in the Testis Capsule

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Cited by 25 •

2011

Human pluripotent stem cells (hPSCs) have the potential to treat a myriad of different diseases. The utility of these cells lies in the fact that they can differentiate into any cell type in the body. Here we describe the teratoma assay, which is used to demonstrate the pluripotence of hPSCs.

Research

JoVE Journal - Medicine

Laparoscopic Anatomical Resection of the Right Anterior Lobe Based on the Laennec Capsule Technique

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Cited by 1 •

2025

This protocol describes a laparoscopic anatomical right anterior sectionectomy utilizing the Laennec capsule concept, combined with comprehensive preoperative therapy. The approach enables precise tumor resection in hepatocellular carcinoma (HCC) cases closely associated with major vascular structures, improving surgical safety, efficacy, and long-term patient outcomes.

Separation of Bacteria by Capsule Amount Using a Discontinuous Density Gradient

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2025

Source: Feltwell, T., et.al. Separating Bacteria by Capsule Amount Using a Discontinuous Density Gradient. J. Vis. Exp. (2019)This video demonstrates the use of a discontinuous density gradient to separate bacterial strains based on capsule amount. By centrifuging a transposon mutant library through the gradient, bacteria with different capsule densities localize to distinct layers. The separated fractions can then be collected for downstream analysis.

Education

JoVE Science Education - Advanced Biology

Microscopy and Staining: Gram, Capsule, and Endospore Staining

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2023

Source: Rhiannon M. LeVeque1, Natalia Martin1, Andrew J. Van Alst1, and Victor J. DiRita1 1 Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, United States of America Bacteria are diverse microorganisms found nearly everywhere on Earth. Many properties help distinguish them from each other, including but not limited to Gram-staining type, shape and arrangement, production of capsule, and formation of spores. To observe these properties, one...

Culturing and Isolating Capsule-Forming Pathogenic Bacterial Strains

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2025

Source: Feltwell, T., et.al. Separating Bacteria by Capsule Amount Using a Discontinuous Density Gradient. J. Vis. Exp. (2019)This video demonstrates the preparation and characterization of bacterial strains with varying capsule production. Pathogenic strains carrying different mutations in capsule-related genes are cultured, grown in liquid media, and subjected to centrifugation to distinguish capsule phenotypes based on pellet density. Buffer treatment is used to wash and stabilize the cells...

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