Compact Cores

Compact cores are densely interconnected groups of brain regions or neurons that form a concentrated network within a larger neural system, helping reveal how communication is organized. Researchers identify them by mapping structural or functional connections and evaluating patterns such as high within-core connectivity, centrality, and strong links among neighboring nodes. In neuroscience, compact-core analysis can highlight hubs that support information integration, distinguish local processing from broader network coordination, and characterize changes associated with development, aging, or neurological disease. These network-level descriptions provide a framework for relating brain architecture to neural function and for comparing connectivity across individuals, species, or experimental conditions.

Compact Cores - Related Videos

Education

JoVE Core - Molecular Biology

The Nucleosome Core Particle

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2020

Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins. The paradox Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...

Compact Bone

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2025

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function. Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...

Research

JoVE Journal - Engineering

Compact Quantum Dots for Single-molecule Imaging

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Cited by 13 •

2012

We describe the preparation of colloidal quantum dots with minimized hydrodynamic size for single-molecule fluorescence imaging. Compared to conventional quantum dots, these nanoparticles are similar in size to globular proteins and are optimized for single-molecule brightness, stability against photodegradation, and resistance to nonspecific binding to proteins and cells.

Compacting Factor test

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2024

The compacting factor test is a method used to assess the workability of concrete. It is especially suitable for concrete mixes containing aggregates up to one and a half inches in size. This test involves specialized equipment consisting of two truncated cone-shaped hoppers and a cylinder, all with polished interior surfaces to minimize friction. The procedure begins by placing concrete into the upper hopper without any compaction. Once filled, the bottom door of this hopper is opened,...

A Protocol for Collecting and Constructing Soil Core Lysimeters

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Cited by 4 •

2016

A detailed method for extraction and assembly of intact soil core lysimeters and their use for study of leachate and associated loss of nutrients from surface applied poultry litter is demonstrated.

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