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February 05, 2022
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This protocol describes the surgical and technical procedures that enable real-time in vivo multiphoton fluorescence imaging of the rodent brain during focused ultrasound and microbubble treatments to increase blood-brain barrier permeability.
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Poon, C., Mühlenpfordt, M., Olsman, M., Kotopoulis, S., de Lange Davies, C., Hynynen, K. Real-Time Intravital Multiphoton Microscopy to Visualize Focused Ultrasound and Microbubble Treatments to Increase Blood-Brain Barrier Permeability. J. Vis. Exp. (180), e62235, doi:10.3791/62235 (2022).
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