Marco C. DeRuiter Department of Anatomy & Embryology Leiden University Medical Center Biography Publications Institution JoVE Articles Marco C. DeRuiter has not added a biography. If you are Marco C. DeRuiter and would like to personalize this page please email our Author Liaison for assistance. Publications Deficient Myocardial Organization and Pathological Fibrosis in Fetal Aortic Stenosis-Association of Prenatal Ultrasound with Postmortem Histology Journal of Cardiovascular Development and Disease. Sep, 2021 | Pubmed ID: 34677190 Placenta Morphology and Biomarkers in Pregnancies with Congenital Heart Disease - A Systematic Review Placenta. 09, 2021 | Pubmed ID: 34388551 The Role of Cell Tracing and Fate Mapping Experiments in Cardiac Outflow Tract Development, New Opportunities Through Emerging Technologies Journal of Cardiovascular Development and Disease. Apr, 2021 | Pubmed ID: 33925811 New Calcification Model for Intact Murine Aortic Valves Journal of Molecular and Cellular Cardiology. 07, 2021 | Pubmed ID: 33744308 Disturbed Nitric Oxide Signalling Gives Rise to Congenital Bicuspid Aortic Valve and Aortopathy Disease Models & Mechanisms. 09, 2020 | Pubmed ID: 32801116 Pulmonary Ductal Coarctation and Left Pulmonary Artery Interruption; Pathology and Role of Neural Crest and Second Heart Field During Development PloS One. 2020 | Pubmed ID: 32413023 Human Epicardium-derived Cells Reinforce Cardiac Sympathetic Innervation Journal of Molecular and Cellular Cardiology. 06, 2020 | Pubmed ID: 32277975 Blood Biomarkers in Patients with Bicuspid Aortic Valve Disease Journal of Cardiology. 09, 2020 | Pubmed ID: 32265086 The Development of the Ascending Aortic Wall in Tricuspid and Bicuspid Aortic Valve: A Process from Maturation to Degeneration Journal of Clinical Medicine. Mar, 2020 | Pubmed ID: 32225051 Rheumatoid Arthritis and Tenosynovitis at the Metatarsophalangeal Joints: An Anatomic and MRI Study of the Forefoot Tendon Sheaths Radiology. 04, 2020 | Pubmed ID: 32043949 In Vivo Detection of Programmed Cell Death During Mouse Heart Development Cell Death and Differentiation. 04, 2020 | Pubmed ID: 31570857 The Role of the Longitudinal Muscle in the Anal Sphincter Complex: Implications for the Intersphincteric Plane in Low Rectal Cancer Surgery? Clinical Anatomy (New York, N.Y.). May, 2020 | Pubmed ID: 31385374 Endothelial Colony Forming Cells As an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve International Journal of Molecular Sciences. Jul, 2019 | Pubmed ID: 31269711 Disruption of RHOA-ROCK Signaling Results in Atrioventricular Block and Disturbed Development of the Putative Atrioventricular Node Anatomical Record (Hoboken, N.J. : 2007). 01, 2019 | Pubmed ID: 30412368 Coronary Anatomy in Turner Syndrome Versus Patients with Isolated Bicuspid Aortic Valves Heart (British Cardiac Society). 05, 2019 | Pubmed ID: 30368485 Coding of Coronary Arterial Origin and Branching in Congenital Heart Disease: The Modified Leiden Convention The Journal of Thoracic and Cardiovascular Surgery. 12, 2018 | Pubmed ID: 30243713 Bicuspid Aortic Valve Formation: Mutation Leads to Abnormal Lineage Patterning of Neural Crest Cells and the Second Heart Field Disease Models & Mechanisms. 10, 2018 | Pubmed ID: 30242109 Endothelial Dysfunction in Pulmonary Arterial Hypertension: Loss of Cilia Length Regulation Upon Cytokine Stimulation Pulmonary Circulation. Apr-Jun, 2018 | Pubmed ID: 29480152 Pulmonary Valve Morphology in Patients with Bicuspid Aortic Valves Pediatric Cardiology. Apr, 2018 | Pubmed ID: 29340729 Coronary Anatomy in Children with Bicuspid Aortic Valves and Associated Congenital Heart Disease Heart (British Cardiac Society). 03, 2018 | Pubmed ID: 28751538 Thoracic Aortic Aneurysm Development in Patients with Bicuspid Aortic Valve: What Is the Role of Endothelial Cells? Frontiers in Physiology. 2017 | Pubmed ID: 29249976 RHOA-ROCK Signalling is Necessary for Lateralization and Differentiation of the Developing Sinoatrial Node Cardiovascular Research. Aug, 2017 | Pubmed ID: 28899000 Twelve Tips for Developing and Delivering a Massive Open Online Course in Medical Education Medical Teacher. Jul, 2017 | Pubmed ID: 28485629 Part and Parcel of the Cardiac Autonomic Nerve System: Unravelling Its Cellular Building Blocks During Development Journal of Cardiovascular Development and Disease. Sep, 2016 | Pubmed ID: 29367572 14-3-3epsilon Controls Multiple Developmental Processes in the Mouse Heart Developmental Dynamics : an Official Publication of the American Association of Anatomists. 11, 2016 | Pubmed ID: 27580238 Diffusion-weighted-preparation (D-prep) MRI As a Future Extension of SPECT/CT Based Surgical Planning for Sentinel Node Procedures in the Head and Neck Area? Oral Oncology. 09, 2016 | Pubmed ID: 27531872 Careful Dissection of the Distal Ureter Is Highly Important in Nerve-sparing Radical Pelvic Surgery: A 3D Reconstruction and Immunohistochemical Characterization of the Vesical Plexus International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Jun, 2016 | Pubmed ID: 27101584 Measuring the Primary Cilium Length: Improved Method for Unbiased High-throughput Analysis Cilia. 2016 | Pubmed ID: 26870322 Coronary Anatomy As Related to Bicuspid Aortic Valve Morphology Heart (British Cardiac Society). 06, 2016 | Pubmed ID: 26864668 The Avian Embryo to Study Development of the Cardiac Conduction System Differentiation; Research in Biological Diversity. Apr-Jun, 2016 | Pubmed ID: 26856662 Common Arterial Trunk and Ventricular Non-compaction in Lrp2 Knockout Mice Indicate a Crucial Role of LRP2 in Cardiac Development Disease Models & Mechanisms. Apr, 2016 | Pubmed ID: 26822476 Deficiency or Inhibition of Lysophosphatidic Acid Receptor 1 Protects Against Hyperoxia-induced Lung Injury in Neonatal Rats Acta Physiologica (Oxford, England). Mar, 2016 | Pubmed ID: 26495902 The Epicardium As Modulator of the Cardiac Autonomic Response During Early Development Journal of Molecular and Cellular Cardiology. Dec, 2015 | Pubmed ID: 26527381 Understanding the Surgical Pitfalls in Total Mesorectal Excision: Investigating the Histology of the Perirectal Fascia and the Pelvic Autonomic Nerves European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. Dec, 2015 | Pubmed ID: 26422586 Understanding Lymphatic Drainage Pathways of the Ovaries to Predict Sites for Sentinel Nodes in Ovarian Cancer International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. Oct, 2015 | Pubmed ID: 26397066 Risk of Damage to the Somatic Innervation of the Penis During the AdVanceProcedure: An Anatomical Study The Journal of Sexual Medicine. Aug, 2015 | Pubmed ID: 26138888 Histopathology of Aortic Complications in Bicuspid Aortic Valve Versus Marfan Syndrome: Relevance for Therapy? Heart and Vessels. Jul, 2015 | Pubmed ID: 26129868 Does the Dorsal Mesenchymal Protrusion Act As a Temporary Pacemaker During Heart Development? The Journal of Biological Chemistry. Mar, 2015 | Pubmed ID: 25795731 The Sinus Venosus Myocardium Contributes to the Atrioventricular Canal: Potential Role During Atrioventricular Node Development? Journal of Cellular and Molecular Medicine. Jun, 2015 | Pubmed ID: 25752780 Abnormal Sinoatrial Node Development Resulting from Disturbed Vascular Endothelial Growth Factor Signaling International Journal of Cardiology. Mar, 2015 | Pubmed ID: 25700200 SLUG is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2015 | Pubmed ID: 25633317 Reply to the Editor The Journal of Thoracic and Cardiovascular Surgery. Nov, 2014 | Pubmed ID: 25444210 Bicuspid Aortic Valve: Phosphorylation of C-Kit and Downstream Targets Are Prognostic for Future Aortopathy European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Nov, 2014 | Pubmed ID: 25161185 Ascending Aorta Dilation in Association with Bicuspid Aortic Valve: a Maturation Defect of the Aortic Wall The Journal of Thoracic and Cardiovascular Surgery. Oct, 2014 | Pubmed ID: 24560417 Reliability and Differentiation of Pelvic Floor Muscle Electromyography Measurements in Healthy Volunteers Using a New Device: the Multiple Array Probe Leiden (MAPLe) Neurourology and Urodynamics. Apr, 2013 | Pubmed ID: 22972554 The Arterial and Cardiac Epicardium in Development, Disease and Repair Differentiation; Research in Biological Diversity. Jul, 2012 | Pubmed ID: 22652098 The Somatic and Autonomic Innervation of the Clitoris; Preliminary Evidence of Sexual Dysfunction After Minimally Invasive Slings The Journal of Sexual Medicine. Jun, 2012 | Pubmed ID: 22489618 Endothelial Colony-forming Cells Show a Mature Transcriptional Response to Shear Stress In Vitro Cellular & Developmental Biology. Animal. Jan, 2012 | Pubmed ID: 22101679 Differential Temporal and Spatial Progerin Expression During Closure of the Ductus Arteriosus in Neonates PloS One. 2011 | Pubmed ID: 21915271 AnatomicalTerms.info: Heading for an Online Solution to the Anatomical Synonym Problem Hurdles in Data-reuse from the Terminologia Anatomica and the Foundational Model of Anatomy and Potentials for Future Development Clinical Anatomy (New York, N.Y.). Oct, 2011 | Pubmed ID: 21678495 Tgfβ/Alk5 Signaling is Required for Shear Stress Induced Klf2 Expression in Embryonic Endothelial Cells Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2011 | Pubmed ID: 21604321 Pkd1-inactivation in Vascular Smooth Muscle Cells and Adaptation to Hypertension Laboratory Investigation; a Journal of Technical Methods and Pathology. Jan, 2011 | Pubmed ID: 20856231 Prenatal Exposure to ApoE Deficiency and Postnatal Hypercholesterolemia Are Associated with Altered Cell-specific Lysine Methyltransferase and Histone Methylation Patterns in the Vasculature The American Journal of Pathology. Feb, 2010 | Pubmed ID: 20035052 Do Not Put Money Where Your Mouth Is! The American Journal of the Medical Sciences. Jan, 2010 | Pubmed ID: 19996732 Insights into the Pathogenesis and Genetic Background of Patency of the Ductus Arteriosus Neonatology. Jun, 2010 | Pubmed ID: 19955832 Podoplanin Deficient Mice Show a RhoA-related Hypoplasia of the Sinus Venosus Myocardium Including the Sinoatrial Node Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jan, 2009 | Pubmed ID: 19097191 Non-invasive Tracking of Avian Development in Vivo by MRI NMR in Biomedicine. May, 2009 | Pubmed ID: 19003815 Maternal Transmission of Risk for Atherosclerosis Current Opinion in Lipidology. Aug, 2008 | Pubmed ID: 18607178 Primary Cilia Sensitize Endothelial Cells for Fluid Shear Stress Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2008 | Pubmed ID: 18297727 Cardiac Malformations and Myocardial Abnormalities in Podoplanin Knockout Mouse Embryos: Correlation with Abnormal Epicardial Development Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2008 | Pubmed ID: 18265012 Endothelial Primary Cilia in Areas of Disturbed Flow Are at the Base of Atherosclerosis Atherosclerosis. Feb, 2008 | Pubmed ID: 17631294 The Influence of Immigrating Extracardiac Cells During Embryonic Development Wiener Klinische Wochenschrift. 2007 | Pubmed ID: 19618591 Origin, Fate, and Function of Epicardium-derived Cells (EPDCs) in Normal and Abnormal Cardiac Development TheScientificWorldJournal. Nov, 2007 | Pubmed ID: 18040540 Pathogenic Sequence for Dissecting Aneurysm Formation in a Hypomorphic Polycystic Kidney Disease 1 Mouse Model Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2007 | Pubmed ID: 17656674 Intrauterine Exposure to Maternal Atherosclerotic Risk Factors Increases the Susceptibility to Atherosclerosis in Adult Life Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2007 | Pubmed ID: 17656671 Nkx2.5-negative Myocardium of the Posterior Heart Field and Its Correlation with Podoplanin Expression in Cells from the Developing Cardiac Pacemaking and Conduction System Anatomical Record (Hoboken, N.J. : 2007). Jan, 2007 | Pubmed ID: 17441204 SOST Expression is Restricted to the Great Arteries During Embryonic and Neonatal Cardiovascular Development Developmental Dynamics : an Official Publication of the American Association of Anatomists. Feb, 2007 | Pubmed ID: 17195180 Transition of Healthy to Diseased Synovial Tissue in Rheumatoid Arthritis is Associated with Gain of Mesenchymal/fibrotic Characteristics Arthritis Research & Therapy. 2006 | Pubmed ID: 17076892 Epicardium-derived Cells Are Important for Correct Development of the Purkinje Fibers in the Avian Heart The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. Dec, 2006 | Pubmed ID: 17075847 Persistent Ductus Arteriosus in the Brown-Norway Inbred Rat Strain Pediatric Research. Oct, 2006 | Pubmed ID: 16940252 Development of the Cardiac Conduction System in Atrioventricular Septal Defect in Human Trisomy 21 Pediatric Research. Sep, 2005 | Pubmed ID: 16148066 Anatomical Basis for Nerve-sparing Radical Hysterectomy: Immunohistochemical Study of the Pelvic Autonomic Nerves Acta Obstetricia Et Gynecologica Scandinavica. Sep, 2005 | Pubmed ID: 16097978 Platelet-derived Growth Factors in the Developing Avian Heart and Maturating Coronary Vasculature Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2005 | Pubmed ID: 15973731 Histological Evaluation of Decellularised Porcine Aortic Valves: Matrix Changes Due to Different Decellularisation Methods European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Apr, 2005 | Pubmed ID: 15784352 Coronary Artery and Orifice Development is Associated with Proper Timing of Epicardial Outgrowth and Correlated Fas-ligand-associated Apoptosis Patterns Circulation Research. Mar, 2005 | Pubmed ID: 15705966 Myocardial Heterogeneity in Permissiveness for Epicardium-derived Cells and Endothelial Precursor Cells Along the Developing Heart Tube at the Onset of Coronary Vascularization The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology. Feb, 2005 | Pubmed ID: 15627984 Basics of Cardiac Development for the Understanding of Congenital Heart Malformations Pediatric Research. Feb, 2005 | Pubmed ID: 15611355 Transforming Growth Factor Beta-SMAD2 Signaling Regulates Aortic Arch Innervation and Development Circulation Research. Nov, 2004 | Pubmed ID: 15528466 Lowering of Pkd1 Expression is Sufficient to Cause Polycystic Kidney Disease Human Molecular Genetics. Dec, 2004 | Pubmed ID: 15496422 Ets-1 and Ets-2 Transcription Factors Are Essential for Normal Coronary and Myocardial Development in Chicken Embryos Circulation Research. Apr, 2003 | Pubmed ID: 12637368 Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing Yang Ge1,2, Lieke van Roon1, H. Sophia Chen1,2, Ruben Methorst1, Martin Paton2, Marco C. DeRuiter1, Szymon M. Kielbasa3, Monique R. M. Jongbloed1,2 1Department of Anatomy & Embryology, Leiden University Medical Center, 2Department of Cardiology, Leiden University Medical Center, 3Department of Medical Statistics and Bioinformatics, Leiden University Medical Center JoVE 63397 Medicina
Low-input Nucleus Isolation and Multiplexing with Barcoded Antibodies of Mouse Sympathetic Ganglia for Single-nucleus RNA Sequencing Yang Ge1,2, Lieke van Roon1, H. Sophia Chen1,2, Ruben Methorst1, Martin Paton2, Marco C. DeRuiter1, Szymon M. Kielbasa3, Monique R. M. Jongbloed1,2 1Department of Anatomy & Embryology, Leiden University Medical Center, 2Department of Cardiology, Leiden University Medical Center, 3Department of Medical Statistics and Bioinformatics, Leiden University Medical Center JoVE 63397 Medicina
