Pierre Fontana Division of Angiology and Haemostasis & Geneva Platelet Group Geneva University Hospitals Biography Publications Institution JoVE Articles Pierre Fontana has not added a biography. If you are Pierre Fontana and would like to personalize this page please email our Author Liaison for assistance. Publications Impact of Rivaroxaban on Point-of-care Assays Thrombosis Research. Mar, 2017 | Pubmed ID: 28343143 Pannexin1 Single Nucleotide Polymorphism and Platelet Reactivity in a Cohort of Cardiovascular Patients Cell Communication & Adhesion. Dec, 2017 | Pubmed ID: 28142297 Management of Direct Oral Anticoagulants in Patients Undergoing Elective Surgeries and Invasive Procedures: Updated Guidelines from the French Working Group on Perioperative Hemostasis (GIHP) - September 2015 Anaesthesia, Critical Care & Pain Medicine. Feb, 2017 | Pubmed ID: 27659969 Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect Frontiers in Pharmacology. 2016 | Pubmed ID: 28066243 Authors' Reply to the Technical Comment from Joelle Michaud and Goranka Tanackovic Swiss Medical Weekly. 2016 | Pubmed ID: 27922174 Correction of Prasugrel-related Bleeding by Prophylactic Transfusion of Human Platelets in a Rabbit Model Transfusion. Oct, 2016 | Pubmed ID: 27546107 Effect of Long-term Adherence to Clopidogrel on the VASP-PRI After Elective Coronary Stent Implantation: a Randomized Controlled Study British Journal of Clinical Pharmacology. Dec, 2016 | Pubmed ID: 27447737 Anti-apolipoprotein A-1 Auto-antibodies As Active Modulators of Atherothrombosis Thrombosis and Haemostasis. Aug, 2016 | Pubmed ID: 27356567 Genetic Testing to Identify Women at Risk of Venous Thromboembolism with Contraceptive Pills: Evidence or Hope-based Tool ? Swiss Medical Weekly. 2016 | Pubmed ID: 27346058 PPM1A Methylation Is Associated With Vascular Recurrence in Aspirin-Treated Patients Stroke. Jul, 2016 | Pubmed ID: 27301936 TRAF3 Epigenetic Regulation Is Associated With Vascular Recurrence in Patients With Ischemic Stroke Stroke. May, 2016 | Pubmed ID: 27026631 Direct Oral Anticoagulants: a Guide for Daily Practice Swiss Medical Weekly. 2016 | Pubmed ID: 26964028 [News in Angiology and Hemostasis] Revue Medicale Suisse. Jan, 2016 | Pubmed ID: 26946695 New Molecular Insights into Modulation of Platelet Reactivity in Aspirin-treated Patients Using a Network-based Approach Human Genetics. Apr, 2016 | Pubmed ID: 26883867 Pharmacogenomics of Oral Antithrombotic Drugs Current Pharmaceutical Design. 2016 | Pubmed ID: 26642774 Modulation of Osteoblast Behavior on TiNxOy Coatings by Altering the N/O Stoichiometry While Maintaining a High Thrombogenic Potential Journal of Biomaterials Applications. Mar, 2016 | Pubmed ID: 26637444 Vascular Risk Levels Affect the Predictive Value of Platelet Reactivity for the Occurrence of MACE in Patients on Clopidogrel. Systematic Review and Meta-analysis of Individual Patient Data Thrombosis and Haemostasis. Apr, 2016 | Pubmed ID: 26607655 Aspirin Response: Differences in Serum Thromboxane B2 Levels Between Clinical Studies Platelets. 2016 | Pubmed ID: 26270593 Reply To: "The Role of Platelets in Liver Regeneration - What Don't We Know?" Journal of Hepatology. Dec, 2015 | Pubmed ID: 26334578 Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review Current Drug Metabolism. 2015 | Pubmed ID: 26179606 A Focus on the Role of Platelets in Liver Regeneration: Do Platelet-endothelial Cell Interactions Initiate the Regenerative Process? Journal of Hepatology. Nov, 2015 | Pubmed ID: 26169159 Lack of Effect of Platelet Transfusions and Desmopressin on Intracranial Bleeding in a Patient Receiving Ticagrelor A & A Case Reports. Jun, 2015 | Pubmed ID: 26050250 Impact of Non-inhibited Platelet Supplementation on Platelet Reactivity in Patients Treated with Prasugrel or Ticagrelor for an Acute Coronary Syndrome: An Ex Vivo Study Platelets. 2015 | Pubmed ID: 25905916 [Last Generation Anti-thrombotic Drugs and Cerebral Hemorrhage ] Revue Medicale Suisse. Jan, 2015 | Pubmed ID: 25845165 Direct Oral Anticoagulants: Efficacy and Safety in Patient Subgroups Swiss Medical Weekly. 2015 | Pubmed ID: 25658756 Antiplatelet Drugs and Platelet Reactivity: is It Time to Halt Clinical Research on Tailored Strategies? Expert Opinion on Pharmacotherapy. Mar, 2015 | Pubmed ID: 25495963 Characterisation of the Influences of Aspirin-acetylation and Glycation on Human Plasma Proteins Journal of Proteomics. Jan, 2015 | Pubmed ID: 25464367 Suspicion of Heparin-induced Thrombocytopenia in Internal Medicine: How Appropriate is the Ordering of Anti-PF4/heparin Antibody Testing? Platelets. 2015 | Pubmed ID: 25275932 Evaluation of the GEM®PCL Plus Point-of-care Device for Neonatal Coagulation Assessment: an Observational Study on Cord Blood Thrombosis Research. Aug, 2014 | Pubmed ID: 24951336 Analysis of 339 Pregnancies in 181 Women with 13 Different Forms of Inherited Thrombocytopenia Haematologica. Aug, 2014 | Pubmed ID: 24763399 [Aspirin: Once or Twice a Day?] Revue Medicale Suisse. Jan, 2014 | Pubmed ID: 24558899 Characterization of the Platelet Granule Proteome: Evidence of the Presence of MHC1 in Alpha-granules Journal of Proteomics. Apr, 2014 | Pubmed ID: 24549006 How to Manage Prasugrel and Ticagrelor in Daily Practice European Journal of Internal Medicine. Mar, 2014 | Pubmed ID: 24529662 Direct Oral Anticoagulants in the Treatment and Long-term Prevention of Venous Thrombo-embolism European Heart Journal. Jul, 2014 | Pubmed ID: 24510637 Fibrinogen Geneva II: a New Congenitally Abnormal Fibrinogen Alpha Chain (Gly17Asp) with a Review of Similar Mutations Resulting in Abnormal Knob A Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis. Apr, 2014 | Pubmed ID: 24389539 [Antiplatelet Agents and Older Patients: Which Drugs and What Evidence?] Revue Medicale Suisse. Nov, 2013 | Pubmed ID: 24308139 [Invasive Procedures and Long-term Anti-coagulation: to Bridge or Not to Bridge?] Revue Medicale Suisse. Oct, 2013 | Pubmed ID: 24298710 Management of Major Bleeding Complications and Emergency Surgery in Patients on Long-term Treatment with Direct Oral Anticoagulants, Thrombin or Factor-Xa Inhibitors: Proposals of the Working Group on Perioperative Haemostasis (GIHP) - March 2013 Archives of Cardiovascular Diseases. Jun-Jul, 2013 | Pubmed ID: 23810130 Tailored Thienopyridine Therapy: No Urgency for CYP2C19 Genotyping Journal of the American Heart Association. Mar, 2013 | Pubmed ID: 23537811 Aspirin for Venous Thromboembolism Prevention and Treatment: a Renewal? Polskie Archiwum Medycyny Wewnetrznej. 2012 | Pubmed ID: 23123525 Antiplatelet Drug Response Status Does Not Predict Recurrent Ischemic Events in Stable Cardiovascular Patients: Results of the Antiplatelet Drug Resistances and Ischemic Events Study Circulation. Jun, 2012 | Pubmed ID: 22615340 Prevalence of Poor Biological Response to Clopidogrel: a Systematic Review Thrombosis and Haemostasis. Mar, 2012 | Pubmed ID: 22273694 Platelet Proteomics Mass Spectrometry Reviews. Mar-Apr, 2012 | Pubmed ID: 22009795 Poor Responsiveness to Antiplatelet Drugs in Acute Coronary Syndromes: Clinical Relevance and Management Cardiovascular Therapeutics. Feb, 2012 | Pubmed ID: 21073667 [Monitoring of Heparins and of Anticoagulants] Revue Medicale Suisse. Oct, 2011 | Pubmed ID: 22073696 Connexin 37 Limits Thrombus Propensity by Downregulating Platelet Reactivity Circulation. Aug, 2011 | Pubmed ID: 21810657 Platelet Reactivity is a Stable and Global Phenomenon in Aspirin-treated Cardiovascular Patients Thrombosis and Haemostasis. Sep, 2011 | Pubmed ID: 21725581 [Evaluating the Biological Efficacy of Clopidogrel: Genotype or Phenotype?] Revue Medicale Suisse. Feb, 2010 | Pubmed ID: 20218180 Effect of Pharmaceutical Interventions Targeting Thromboxane Receptors and Thromboxane Synthase in Cardiovascular and Renal Diseases Future Cardiology. Sep, 2009 | Pubmed ID: 19715412 Diagnosis of Mild Bleeding Disorders Swiss Medical Weekly. Jun, 2009 | Pubmed ID: 19529990 No Influence of the VAMP8 Rs1010 Single Nucleotide Polymorphism on Platelet Functions in Vitro Journal of Cellular and Molecular Medicine. Mar, 2009 | Pubmed ID: 19374688 Acute Coronary Syndrome and Its Antithrombotic Treatment: Focus on Aspirin and Clopidogrel Resistance Current Vascular Pharmacology. Apr, 2009 | Pubmed ID: 19356003 Cell-derived Microparticles in Haemostasis and Vascular Medicine Thrombosis and Haemostasis. Mar, 2009 | Pubmed ID: 19277403 [The New Antithrombotics in 2009] Revue Medicale Suisse. Feb, 2009 | Pubmed ID: 19271646 [A Reference to Know: the 2008 Chest Supplement on Antithrombotic Agents] Revue Medicale Suisse. Jan, 2009 | Pubmed ID: 19238928 Intercellular Communication in Atherosclerosis Physiology (Bethesda, Md.). Feb, 2009 | Pubmed ID: 19196650 Aspirin Response Variability Assessed with the PFA-100 Device Thrombosis and Haemostasis. May, 2008 | Pubmed ID: 18449432 [Frequently Asked Questions on Clopidogrel Treatment: Indications, Resistance, and Biological Evaluation in Vascular Patients] Revue Medicale Suisse. Feb, 2008 | Pubmed ID: 18386673 Laboratory-defined Aspirin Resistance and Recurrent Cardiovascular Events Archives of Internal Medicine. Mar, 2008 | Pubmed ID: 18332305 Biological Effect of Increased Maintenance Dose of Clopidogrel in Cardiovascular Outpatients and Influence of the Cytochrome P450 2C19*2 Allele on Clopidogrel Responsiveness Thrombosis Research. 2008 | Pubmed ID: 17681590 Identification of Functional Polymorphisms of the Thromboxane A2 Receptor Gene in Healthy Volunteers Thrombosis and Haemostasis. Sep, 2006 | Pubmed ID: 16953279 Common Sequence Variations in the P2Y12 and CYP3A5 Genes Do Not Explain the Variability in the Inhibitory Effects of Clopidogrel Therapy Platelets. Jun, 2006 | Pubmed ID: 16769602 Physiological Plasma Gas6 Levels Do Not Influence Platelet Aggregation Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2006 | Pubmed ID: 16484600 The Thrombomodulin-1208/-1209delTT Gene Promoter Polymorphism Does Not Affect Basal or LPS-dependent Monocyte TM MRNA Transcription in Healthy Volunteers Thrombosis and Haemostasis. Sep, 2005 | Pubmed ID: 16268494 Prolonged Treatment of Massive Postpartum Haemorrhage with Recombinant Factor VIIa: Case Report and Review of the Literature BJOG : an International Journal of Obstetrics and Gynaecology. Mar, 2004 | Pubmed ID: 14961895 The TF-603A/G Gene Promoter Polymorphism and Circulating Monocyte Tissue Factor Gene Expression in Healthy Volunteers Thrombosis and Haemostasis. Feb, 2004 | Pubmed ID: 14961150 Skin Necrosis is a Clinical Manifestation of Low-molecular Weight Heparin-induced Thrombocytopenia Thrombosis and Haemostasis. Jan, 2004 | Pubmed ID: 14691586 [Study of Primary Hemostasis in Vitro with the Platelet Function Analyzer (PFA-100)] Revue Medicale De La Suisse Romande. Aug, 2003 | Pubmed ID: 15095645 P2Y12 H2 Haplotype is Associated with Peripheral Arterial Disease: a Case-control Study Circulation. Dec, 2003 | Pubmed ID: 14662702 Adenosine Diphosphate-induced Platelet Aggregation is Associated with P2Y12 Gene Sequence Variations in Healthy Subjects Circulation. Aug, 2003 | Pubmed ID: 12912815 An Intronic Polymorphism in the PAR-1 Gene is Associated with Platelet Receptor Density and the Response to SFLLRN Blood. Mar, 2003 | Pubmed ID: 12406873 Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation Filippo Molica1, Séverine Nolli2, Pierre Fontana2, Brenda Renata Kwak1 1Department of Pathology and Immunology, University of Geneva, 2Division of Angiology and Haemostasis & Geneva Platelet Group, Geneva University Hospitals JoVE 55525 Medicina
Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation Filippo Molica1, Séverine Nolli2, Pierre Fontana2, Brenda Renata Kwak1 1Department of Pathology and Immunology, University of Geneva, 2Division of Angiology and Haemostasis & Geneva Platelet Group, Geneva University Hospitals JoVE 55525 Medicina