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Bepaling van de eindsystolische en einddiastolische druk-volumerelaties in een muizenhartfalenmodel en transoesofageale stimulatie

Exploring HR-Dependent Cardiac Performance Using an Atrial-Pacing Protocol

Article DOI: 10.3791/200330-v • 03:15 min • July 21st, 2023
July 21st, 2023 •
1,2, 1,3
1Department of Cardiovascular Medicine, The University of Tokyo Hospital, 2Department of Therapeutic Strategy for Heart Failure, Graduate School of Medicine, The University of Tokyo, 3Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions

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Pacing-gecontroleerde procedure beoordeling hartslagafhankelijke diastolische functies Muizen hartfalenmodellen Hartfalen met behouden ejectiefractie HFpEF Diastolische disfunctie inspanningsintolerantie Hemodynamische tests MRI Fundamenteel onderzoek Muismodellen Loopbandinspanningstest Lichaamsgewicht Skeletspierkracht Mentale toestand Atrial-pacing-protocol Hartslagveranderingen Diastolische prestaties Muismodel van HFpEF Verdoving Intuberen Druk-volume lusanalyse Geleidingskatheter atriale stimulatiekatheter ivabradine HR-stappen Bpm (slagen per minuut) diastolische stoornis metabolisch geïnduceerd HFpEF-model relaxatietijdconstante (Tau) einddiastolische druk-volumerelatie (EDPVR)
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