Avaliação de agentes de indução Hyperpermeability vasculares na pele com o ensaio de milhas
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June 19, 2018
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Aqui, apresentamos um protocolo para medir o vazamento vascular induzido pela administração intradérmica de agentes de promoção de permeabilidade na pele murino. Esta técnica pode ser usada para determinar a capacidade das moléculas de promover ou inibir vazamento vascular ou para estudar os mecanismos moleculares que regulam a permeabilidade vascular.
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Brash, J. T., Ruhrberg, C., Fantin, A. Evaluating Vascular Hyperpermeability-inducing Agents in the Skin with the Miles Assay. J. Vis. Exp. (136), e57524, doi:10.3791/57524 (2018).
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